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Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

  • Myungjin Jo
  • Ah Young Chung
  • Nozomu Yachie
  • Minchul Seo
  • Hyejin Jeon
  • Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
  • ... [+4 authors] ...,
  • Marc Vidal
  • Hae Chul Park
  • Frederick P. Roth
  • Kyoungho Suk
  • First Published June 8, 2017
Research

Chlamydia trachomatis show ancient diversification followed by contemporary mixing and recent lineage expansion" > Comprehensive global genome dynamics of Chlamydia trachomatis show ancient diversification followed by contemporary mixing and recent lineage expansion

  • James Hadfield
  • Simon R. Harris
  • Helena M.B. Seth-Smith
  • Surendra Parmar
  • Patiyan Andersson
  • Philip M. Giffard Julius Schachter Jeanne Moncada Louise Ellison María Lucía Gallo Vaulet Marcelo Rodríguez Fermepin Frans Radebe Suyapa Mendoza Sander Ouburg Servaas A. Morré Konrad Sachse Mirja Puolakkainen Suvi J. Korhonen Chris Sonnex Rebecca Wiggins Hamid Jalal Tamara Brunelli Patrizia Casprini Rachel Pitt Cathy Ison Alevtina Savicheva Elena Shipitsyna Ronza Hadad Laszlo Kari Matthew J. Burton David Mabey Anthony W. Solomon David Lewis Peter Marsh
  • ... [+29 authors] ...,
  • Magnus Unemo
  • Ian N. Clarke
  • Julian Parkhill
  • Nicholas R. Thomson
  • First Published June 6, 2017
Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

  • Song Sun
  • Fan Yang
  • Guihong Tan
  • Michael Costanzo
  • Rose Oughtred
  • Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
  • ... [+10 authors] ...,
  • Brenda J. Andrews
  • Charles Boone
  • Kara Dolinski
  • Frederick P. Roth
  • First Published March 14, 2016
Method

Chlamydia trachomatis directly from clinical samples without culture" > Whole-genome sequences of Chlamydia trachomatis directly from clinical samples without culture

  • Helena M.B. Seth-Smith
  • Simon R. Harris
  • Rachel J. Skilton
  • Frans M. Radebe
  • Daniel Golparian
  • Elena Shipitsyna Pham Thanh Duy Paul Scott Lesley T. Cutcliffe Colette O’Neill Surendra Parmar Rachel Pitt Stephen Baker Catherine A. Ison Peter Marsh Hamid Jalal David A. Lewis
  • ... [+12 authors] ...,
  • Magnus Unemo
  • Ian N. Clarke
  • Julian Parkhill
  • Nicholas R. Thomson
  • First Published March 22, 2013
Letter

Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype" > Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

  • Robert A. Kingsley
  • Chisomo L. Msefula
  • Nicholas R. Thomson
  • Samuel Kariuki
  • Kathryn E. Holt
  • Melita A. Gordon David Harris Louise Clarke Sally Whitehead Vartul Sangal Kevin Marsh Mark Achtman Malcolm E. Molyneux Martin Cormican
  • ... [+9 authors] ...,
  • Julian Parkhill
  • Calman A. MacLennan
  • Robert S. Heyderman
  • Gordon Dougan
  • First Published November 9, 2009
Resource

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

  • Kourosh Salehi-Ashtiani
  • Chenwei Lin
  • Tong Hao
  • Yun Shen
  • David Szeto
  • Xinping Yang Lila Ghamsari HanJoo Lee Changyu Fan Ryan R. Murray Stuart Milstein Nenad Svrzikapa
  • ... [+7 authors] ...,
  • Michael E. Cusick
  • Frederick P. Roth
  • David E. Hill
  • Marc Vidal
  • First Published October 2, 2009
Resource

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

  • Gabriel Markson
  • Christina Kiel
  • Russell Hyde
  • Stephanie Brown
  • Panagoula Charalabous
  • Anja Bremm Jennifer Semple Jonathan Woodsmith Simon Duley Kourosh Salehi-Ashtiani Marc Vidal
  • ... [+6 authors] ...,
  • David Komander
  • Luis Serrano
  • Paul Lehner
  • Christopher M. Sanderson
  • First Published June 23, 2009
Methods

Shifted Transversal Design smart-pooling for high coverage interactome mapping

  • Xiaofeng Xin
  • Jean-François Rual
  • Tomoko Hirozane-Kishikawa
  • David E. Hill
  • Marc Vidal
  • Charles Boone
  • Nicolas Thierry-Mieg
  • First Published May 15, 2009
ARTICLE

Pseudomonas aeruginosa" > Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa

  • Craig Winstanley
  • Morgan G.I. Langille
  • Joanne L. Fothergill
  • Irena Kukavica-Ibrulj
  • Catherine Paradis-Bleau
  • François Sanschagrin Nicholas R. Thomson Geoff L. Winsor Michael A. Quail Nicola Lennard Alexandra Bignell Louise Clarke Kathy Seeger David Saunders David Harris
  • ... [+10 authors] ...,
  • Julian Parkhill
  • Robert E.W. Hancock
  • Fiona S.L. Brinkman
  • Roger C. Levesque
  • First Published December 1, 2008
LETTER

Salmonella Enteritidis PT4 and Salmonella Gallinarum 287/91 provides insights into evolutionary and host adaptation pathways" > Comparative genome analysis of Salmonella Enteritidis PT4 and Salmonella Gallinarum 287/91 provides insights into evolutionary and host adaptation pathways

  • Nicholas R. Thomson
  • Debra J. Clayton
  • Daniel Windhorst
  • Georgios Vernikos
  • Susanne Davidson
  • Carol Churcher Michael A. Quail Mark Stevens Michael A. Jones Michael Watson Andy Barron Abigail Layton Derek Pickard Robert A. Kingsley Alex Bignell Louise Clark Barbara Harris Doug Ormond Zahra Abdellah Karen Brooks Inna Cherevach Tracey Chillingworth John Woodward Halina Norberczak Angela Lord Claire Arrowsmith Kay Jagels Sharon Moule Karen Mungall Mandy Sanders Sally Whitehead Jose A. Chabalgoity Duncan Maskell Tom Humphrey
  • ... [+29 authors] ...,
  • Mark Roberts
  • Paul A. Barrow
  • Gordon Dougan
  • Julian Parkhill
  • First Published June 26, 2008
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