Search | Genome Research

Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

Myungjin Jo
Ah Young Chung
Nozomu Yachie
Minchul Seo
Hyejin Jeon
Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
... [+4 authors] ...,
Marc Vidal
Hae Chul Park
Frederick P. Roth
Kyoungho Suk

First Published June 8, 2017

Method

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

Jonathan S. Brammeld
Mia Petljak
Inigo Martincorena
Steven P. Williams
Luz Garcia Alonso
Alba Dalmases Beatriz Bellosillo Carla Daniela Robles-Espinoza Stacey Price Syd Barthorpe Patrick Tarpey Constantine Alifrangis Graham Bignell Joana Vidal Jamie Young Lucy Stebbings Kathryn Beal Michael R. Stratton Julio Saez-Rodriguez
... [+14 authors] ...,
Mathew Garnett
Clara Montagut
Francesco Iorio
Ultan McDermott

First Published February 8, 2017

Corrigendum

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Young Seok Ju
Jose M.C. Tubio
William Mifsud
Beiyuan Fu
Helen R. Davies
Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
... [+39 authors] ...,
Fengtang Yang
Serena Nik-Zainal
Peter J. Campbell
Michael R. Stratton

First Published May 2, 2016

Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

Song Sun
Fan Yang
Guihong Tan
Michael Costanzo
Rose Oughtred
Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
... [+10 authors] ...,
Brenda J. Andrews
Charles Boone
Kara Dolinski
Frederick P. Roth

First Published March 14, 2016

Research

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Young Seok Ju
Jose M.C. Tubio
William Mifsud
Beiyuan Fu
Helen R. Davies
Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
... [+39 authors] ...,
Fengtang Yang
Serena Nik-Zainal
Peter J. Campbell
Michael R. Stratton

First Published May 11, 2015

Research

C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency" > C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

Bettina Meier
Susanna L. Cooke
Joerg Weiss
Aymeric P. Bailly
Ludmil B. Alexandrov
John Marshall Keiran Raine Mark Maddison
... [+3 authors] ...,
Elizabeth Anderson
Michael R. Stratton
Anton Gartner
Peter J. Campbell

First Published July 16, 2014

Method

Estimation of rearrangement phylogeny for cancer genomes

Chris D. Greenman
Erin D. Pleasance
Scott Newman
Fengtang Yang
Beiyuan Fu
Serena Nik-Zainal David Jones King Wai Lau Nigel Carter
... [+4 authors] ...,
Paul A.W. Edwards
P. Andrew Futreal
Michael R. Stratton
Peter J. Campbell

First Published October 12, 2011

Resource

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

Kourosh Salehi-Ashtiani
Chenwei Lin
Tong Hao
Yun Shen
David Szeto
Xinping Yang Lila Ghamsari HanJoo Lee Changyu Fan Ryan R. Murray Stuart Milstein Nenad Svrzikapa
... [+7 authors] ...,
Michael E. Cusick
Frederick P. Roth
David E. Hill
Marc Vidal

First Published October 2, 2009

Resource

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

Gabriel Markson
Christina Kiel
Russell Hyde
Stephanie Brown
Panagoula Charalabous
Anja Bremm Jennifer Semple Jonathan Woodsmith Simon Duley Kourosh Salehi-Ashtiani Marc Vidal
... [+6 authors] ...,
David Komander
Luis Serrano
Paul Lehner
Christopher M. Sanderson

First Published June 23, 2009

Methods

Shifted Transversal Design smart-pooling for high coverage interactome mapping

Xiaofeng Xin
Jean-François Rual
Tomoko Hirozane-Kishikawa
David E. Hill
Marc Vidal
Charles Boone
Nicolas Thierry-Mieg

First Published May 15, 2009

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Your search for returned 30 results

Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

Method

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

Corrigendum

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

Research

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Research

C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency" > C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

Method

Estimation of rearrangement phylogeny for cancer genomes

Resource

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

Resource

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

Methods

Shifted Transversal Design smart-pooling for high coverage interactome mapping

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Your search for returned 30 results

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