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An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms

Javier Tapial
Kevin C.H. Ha
Timothy Sterne-Weiler
André Gohr
Ulrich Braunschweig
Antonio Hermoso-Pulido Mathieu Quesnel-Vallières Jon Permanyer Reza Sodaei Yamile Marquez Luca Cozzuto Xinchen Wang Melisa Gómez-Velázquez Teresa Rayon
... [+9 authors] ...,
Miguel Manzanares
Julia Ponomarenko
Benjamin J. Blencowe
Manuel Irimia

First Published August 30, 2017

Widespread intron retention in mammals functionally tunes transcriptomes

Ulrich Braunschweig
Nuno L. Barbosa-Morais
Qun Pan
Emil N. Nachman
Babak Alipanahi
Thomas Gonatopoulos-Pournatzis
Brendan Frey
Manuel Irimia
Benjamin J. Blencowe

First Published September 25, 2014

cis-regulatory constraints" > Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints

Manuel Irimia
Juan J. Tena
Maria S. Alexis
Ana Fernandez-Miñan
Ignacio Maeso
Ozren Bogdanović
... [+1 authors] ...,
Elisa de la Calle-Mustienes
Scott W. Roy
José L. Gómez-Skarmeta
Hunter B. Fraser

First Published June 21, 2012

An ancient genomic regulatory block conserved across bilaterians and its dismantling in tetrapods by retrogene replacement

Ignacio Maeso
Manuel Irimia
Juan J. Tena
Esther González-Pérez
David Tran
Vydianathan Ravi
... [+1 authors] ...,
Byrappa Venkatesh
Sonsoles Campuzano
José Luis Gómez-Skarmeta
Jordi Garcia-Fernàndez

First Published January 10, 2012

Complex selection on 5′ splice sites in intron-rich organisms

Manuel Irimia
Scott William Roy
Daniel E. Neafsey
Josep F. Abril
Jordi Garcia-Fernandez
Eugene V. Koonin

First Published September 10, 2009