Search | Genome Research

Method

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

Jonathan S. Brammeld
Mia Petljak
Inigo Martincorena
Steven P. Williams
Luz Garcia Alonso
Alba Dalmases Beatriz Bellosillo Carla Daniela Robles-Espinoza Stacey Price Syd Barthorpe Patrick Tarpey Constantine Alifrangis Graham Bignell Joana Vidal Jamie Young Lucy Stebbings Kathryn Beal Michael R. Stratton Julio Saez-Rodriguez
... [+14 authors] ...,
Mathew Garnett
Clara Montagut
Francesco Iorio
Ultan McDermott

First Published February 8, 2017

Corrigendum

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Young Seok Ju
Jose M.C. Tubio
William Mifsud
Beiyuan Fu
Helen R. Davies
Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
... [+39 authors] ...,
Fengtang Yang
Serena Nik-Zainal
Peter J. Campbell
Michael R. Stratton

First Published May 2, 2016

Research

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Young Seok Ju
Jose M.C. Tubio
William Mifsud
Beiyuan Fu
Helen R. Davies
Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
... [+39 authors] ...,
Fengtang Yang
Serena Nik-Zainal
Peter J. Campbell
Michael R. Stratton

First Published May 11, 2015

Research

C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency" > C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

Bettina Meier
Susanna L. Cooke
Joerg Weiss
Aymeric P. Bailly
Ludmil B. Alexandrov
John Marshall Keiran Raine Mark Maddison
... [+3 authors] ...,
Elizabeth Anderson
Michael R. Stratton
Anton Gartner
Peter J. Campbell

First Published July 16, 2014

Research

D. melanogaster is found at specific short motifs and is independent of DNMT2 activity" > Genome methylation in D. melanogaster is found at specific short motifs and is independent of DNMT2 activity

Sachiko Takayama
Joseph Dhahbi
Adam Roberts
Guanxiong Mao
Seok-Jin Heo
Lior Pachter
David I.K. Martin
Dario Boffelli

First Published February 20, 2014

Method

Estimation of rearrangement phylogeny for cancer genomes

Chris D. Greenman
Erin D. Pleasance
Scott Newman
Fengtang Yang
Beiyuan Fu
Serena Nik-Zainal David Jones King Wai Lau Nigel Carter
... [+4 authors] ...,
Paul A.W. Edwards
P. Andrew Futreal
Michael R. Stratton
Peter J. Campbell

First Published October 12, 2011

Research

Phyloepigenomic comparison of great apes reveals a correlation between somatic and germline methylation states

David I.K. Martin
Meromit Singer
Joseph Dhahbi
Guanxiong Mao
Lu Zhang
Gary P. Schroth
Lior Pachter
Dario Boffelli

First Published September 9, 2011

LETTER

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

Graham R. Bignell
Thomas Santarius
Jessica C.M. Pole
Adam P. Butler
Janet Perry
Erin Pleasance Chris Greenman Andrew Menzies Sheila Taylor Sarah Edkins Peter Campbell Michael Quail Bob Plumb Lucy Matthews Kirsten McLay Paul A.W. Edwards
... [+11 authors] ...,
Jane Rogers
Richard Wooster
P. Andrew Futreal
Michael R. Stratton

First Published August 3, 2007

ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

Elliott H. Margulies
Gregory M. Cooper
George Asimenos
Daryl J. Thomas
Colin N. Dewey
Adam Siepel Ewan Birney Damian Keefe Ariel S. Schwartz Minmei Hou James Taylor Sergey Nikolaev Juan I. Montoya-Burgos Ari Löytynoja Simon Whelan Fabio Pardi Tim Massingham James B. Brown Peter Bickel Ian Holmes James C. Mullikin Abel Ureta-Vidal Benedict Paten Eric A. Stone Kate R. Rosenbloom W. James Kent Gerard G. Bouffard Xiaobin Guan Nancy F. Hansen Jacquelyn R. Idol Valerie V.B. Maduro Baishali Maskeri Jennifer C. McDowell Morgan Park Pamela J. Thomas Alice C. Young Robert W. Blakesley Donna M. Muzny Erica Sodergren David A. Wheeler Kim C. Worley Huaiyang Jiang George M. Weinstock Richard A. Gibbs Tina Graves Robert Fulton Elaine R. Mardis Richard K. Wilson Michele Clamp James Cuff Sante Gnerre David B. Jaffe Jean L. Chang Kerstin Lindblad-Toh Eric S. Lander Angie Hinrichs Heather Trumbower Hiram Clawson Ann Zweig Robert M. Kuhn Galt Barber Rachel Harte Donna Karolchik Matthew A. Field Richard A. Moore Carrie A. Matthewson Jacqueline E. Schein Marco A. Marra Stylianos E. Antonarakis Serafim Batzoglou Nick Goldman Ross Hardison David Haussler
... [+68 authors] ...,
Webb Miller
Lior Pachter
Eric D. Green
Arend Sidow

First Published June 13, 2007

Methods

Decoding the fine-scale structure of a breast cancer genome and transcriptome

Stanislav Volik
Benjamin J. Raphael
Guiqing Huang
Michael R. Stratton
Graham Bignel
John Murnane John H. Brebner Krystyna Bajsarowicz Pamela L. Paris Quanzhou Tao David Kowbel Anna Lapuk Dmitri A. Shagin Irina A. Shagina Joe W. Gray
... [+10 authors] ...,
Jan-Fang Cheng
Pieter J. de Jong
Pavel Pevzner
Colin Collins

First Published February 3, 2006

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Your search for returned 25 results

Method

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

Corrigendum

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Research

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Research

C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency" > C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

Research

D. melanogaster is found at specific short motifs and is independent of DNMT2 activity" > Genome methylation in D. melanogaster is found at specific short motifs and is independent of DNMT2 activity

Method

Estimation of rearrangement phylogeny for cancer genomes

Research

Phyloepigenomic comparison of great apes reveals a correlation between somatic and germline methylation states

LETTER

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

Methods

Decoding the fine-scale structure of a breast cancer genome and transcriptome

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Your search for returned 25 results

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