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Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation

  • First Published December 5, 2024

Analysis of a cell-free DNA–based cancer screening cohort links fragmentomic profiles, nuclease levels, and plasma DNA concentrations

  • First Published November 27, 2024

Genomic origin, fragmentomics, and transcriptional properties of long cell-free DNA molecules in human plasma

  • First Published February 26, 2024

Nuclease deficiencies alter plasma cell-free DNA methylation profiles

  • First Published September 1, 2021

Detection and characterization of jagged ends of double-stranded DNA in plasma

  • First Published August 14, 2020

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma

  • First Published June 27, 2019

Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin

  • First Published February 26, 2019

TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data

  • First Published July 24, 2014

Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm

  • First Published June 26, 2013

Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

  • First Published June 26, 2013
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