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Research

Mitotic chromosomes harbor cell type– and species-specific structural features within a universal loop array conformation

  • Marlies E. Oomen
  • A. Nicole Fox
  • Inma Gonzalez
  • Amandine Molliex
  • Thaleia Papadopoulou
  • Pablo Navarro
  • Job Dekker
  • First Published June 6, 2025
Research

Revisiting chromatin packaging in mouse sperm

  • Qiangzong Yin
  • Chih-Hsiang Yang
  • Olga S. Strelkova
  • Jingyi Wu
  • Yu Sun
  • Sneha Gopalan Liyan Yang Job Dekker
  • ... [+3 authors] ...,
  • Thomas G. Fazzio
  • Xin Zhiguo Li
  • Johan Gibcus
  • Oliver J. Rando
  • First Published December 21, 2023
Research

CTCF sites display cell cycle–dependent dynamics in factor binding and nucleosome positioning

  • Marlies E. Oomen
  • Anders S. Hansen
  • Yu Liu
  • Xavier Darzacq
  • Job Dekker
  • First Published January 17, 2019
Method

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

  • Jonathan S. Brammeld
  • Mia Petljak
  • Inigo Martincorena
  • Steven P. Williams
  • Luz Garcia Alonso
  • Alba Dalmases Beatriz Bellosillo Carla Daniela Robles-Espinoza Stacey Price Syd Barthorpe Patrick Tarpey Constantine Alifrangis Graham Bignell Joana Vidal Jamie Young Lucy Stebbings Kathryn Beal Michael R. Stratton Julio Saez-Rodriguez
  • ... [+14 authors] ...,
  • Mathew Garnett
  • Clara Montagut
  • Francesco Iorio
  • Ultan McDermott
  • First Published February 8, 2017
Research

SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells

  • A. Rasim Barutcu
  • Bryan R. Lajoie
  • Andrew J. Fritz
  • Rachel P. McCord
  • Jeffrey A. Nickerson
  • Andre J. van Wijnen Jane B. Lian
  • ... [+2 authors] ...,
  • Janet L. Stein
  • Job Dekker
  • Gary S. Stein
  • Anthony N. Imbalzano
  • First Published July 19, 2016
Corrigendum

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

  • Young Seok Ju
  • Jose M.C. Tubio
  • William Mifsud
  • Beiyuan Fu
  • Helen R. Davies
  • Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
  • ... [+39 authors] ...,
  • Fengtang Yang
  • Serena Nik-Zainal
  • Peter J. Campbell
  • Michael R. Stratton
  • First Published May 2, 2016
Research

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

  • Young Seok Ju
  • Jose M.C. Tubio
  • William Mifsud
  • Beiyuan Fu
  • Helen R. Davies
  • Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
  • ... [+39 authors] ...,
  • Fengtang Yang
  • Serena Nik-Zainal
  • Peter J. Campbell
  • Michael R. Stratton
  • First Published May 11, 2015
Research

Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin

  • Elizabeth Ing-Simmons
  • Vlad C. Seitan
  • Andre J. Faure
  • Paul Flicek
  • Thomas Carroll
  • Job Dekker
  • Amanda G. Fisher
  • Boris Lenhard
  • Matthias Merkenschlager
  • First Published February 12, 2015
Research

C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency" > C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

  • Bettina Meier
  • Susanna L. Cooke
  • Joerg Weiss
  • Aymeric P. Bailly
  • Ludmil B. Alexandrov
  • John Marshall Keiran Raine Mark Maddison
  • ... [+3 authors] ...,
  • Elizabeth Anderson
  • Michael R. Stratton
  • Anton Gartner
  • Peter J. Campbell
  • First Published July 16, 2014
Research

Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments

  • Vlad C. Seitan
  • Andre J. Faure
  • Ye Zhan
  • Rachel Patton McCord
  • Bryan R. Lajoie
  • Elizabeth Ing-Simmons Boris Lenhard Luca Giorgetti Edith Heard
  • ... [+4 authors] ...,
  • Amanda G. Fisher
  • Paul Flicek
  • Job Dekker
  • Matthias Merkenschlager
  • First Published September 3, 2013
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