Perspective
Applications of single-cell genomics and computational strategies to study common disease and population-level variation
- First Published October 1, 2021
Method
A joint deep learning model enables simultaneous batch effect correction, denoising, and clustering in single-cell transcriptomics
- First Published May 25, 2021
Resource
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly
- First Published April 10, 2017
Method
Using reference-free compressed data structures to analyze sequencing reads from thousands of human genomes
- First Published December 16, 2016
Resource
Assemblathon 1: A competitive assessment of de novo short read assembly methods
- First Published September 16, 2011
Method
Revealing the genetic structure of a trait by sequencing a population under selection
- First Published March 21, 2011
Methods
PennCNV: An integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data
- First Published October 5, 2007