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MAPLE enables ultrasensitive detection of low-frequency cfDNA methylation haplotypes using short capture probes with cost-efficient performance

  • First Published June 16, 2026
Research

Closing the gaps, and improving somatic structural variant analysis and benchmarking using CHM13-T2T

  • First Published March 17, 2025
Research

Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation

  • First Published December 5, 2024
Method

Targeted, programmable, and precise tandem duplication in the mammalian genome

  • First Published June 9, 2023
Research

Long-read sequencing of 111 rice genomes reveals significantly larger pan-genomes

  • First Published April 8, 2022
Method

Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA

  • First Published June 17, 2021
Method

Predicting unrecognized enhancer-mediated genome topology by an ensemble machine learning model

  • First Published November 12, 2020
Method

Defining cell-type specificity at the transcriptional level in human disease

  • First Published August 15, 2013
Method

Spark: A navigational paradigm for genomic data exploration

  • First Published September 7, 2012
Research

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver

  • First Published June 15, 2010
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