Research
Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation
- First Published December 5, 2024
Method
Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA
- First Published June 17, 2021
Research
High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma
- First Published June 27, 2019
Method
Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq
- First Published January 19, 2016
Method
TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data
- First Published July 24, 2014
Method
Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins
- First Published April 2, 2014
Method
Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
- First Published November 19, 2013
Method
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
- First Published June 26, 2013
Method
Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods
- First Published June 26, 2013