Search | Genome Research

Method

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

Jonathan S. Brammeld
Mia Petljak
Inigo Martincorena
Steven P. Williams
Luz Garcia Alonso
Alba Dalmases Beatriz Bellosillo Carla Daniela Robles-Espinoza Stacey Price Syd Barthorpe Patrick Tarpey Constantine Alifrangis Graham Bignell Joana Vidal Jamie Young Lucy Stebbings Kathryn Beal Michael R. Stratton Julio Saez-Rodriguez
... [+14 authors] ...,
Mathew Garnett
Clara Montagut
Francesco Iorio
Ultan McDermott

First Published February 8, 2017

Corrigendum

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Young Seok Ju
Jose M.C. Tubio
William Mifsud
Beiyuan Fu
Helen R. Davies
Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
... [+39 authors] ...,
Fengtang Yang
Serena Nik-Zainal
Peter J. Campbell
Michael R. Stratton

First Published May 2, 2016

Research

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Young Seok Ju
Jose M.C. Tubio
William Mifsud
Beiyuan Fu
Helen R. Davies
Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
... [+39 authors] ...,
Fengtang Yang
Serena Nik-Zainal
Peter J. Campbell
Michael R. Stratton

First Published May 11, 2015

Research

C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency" > C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

Bettina Meier
Susanna L. Cooke
Joerg Weiss
Aymeric P. Bailly
Ludmil B. Alexandrov
John Marshall Keiran Raine Mark Maddison
... [+3 authors] ...,
Elizabeth Anderson
Michael R. Stratton
Anton Gartner
Peter J. Campbell

First Published July 16, 2014

Method

Estimation of rearrangement phylogeny for cancer genomes

Chris D. Greenman
Erin D. Pleasance
Scott Newman
Fengtang Yang
Beiyuan Fu
Serena Nik-Zainal David Jones King Wai Lau Nigel Carter
... [+4 authors] ...,
Paul A.W. Edwards
P. Andrew Futreal
Michael R. Stratton
Peter J. Campbell

First Published October 12, 2011

Letter

Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level

Alexander W. Bruce
Andrés J. López-Contreras
Paul Flicek
Thomas A. Down
Pawandeep Dhami
Shane C. Dillon Christoph M. Koch
... [+2 authors] ...,
Cordelia F. Langford
Ian Dunham
Robert M. Andrews
David Vetrie

First Published April 28, 2009

LETTER

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

David S. Johnson
Wei Li
D. Benjamin Gordon
Arindam Bhattacharjee
Bo Curry
Jayati Ghosh Leonardo Brizuela Jason S. Carroll Myles Brown Paul Flicek Christoph M. Koch Ian Dunham Mark Bieda Xiaoqin Xu Peggy J. Farnham Philipp Kapranov David A. Nix Thomas R. Gingeras Xinmin Zhang Heather Holster Nan Jiang Roland D. Green Jun S. Song Scott A. McCuine Elizabeth Anton Loan Nguyen Nathan D. Trinklein Zhen Ye Keith Ching David Hawkins Bing Ren Peter C. Scacheri Joel Rozowsky Alexander Karpikov Ghia Euskirchen Sherman Weissman Mark Gerstein Michael Snyder Annie Yang Zarmik Moqtaderi Heather Hirsch Hennady P. Shulha Yutao Fu Zhiping Weng
... [+39 authors] ...,
Kevin Struhl
Richard M. Myers
Jason D. Lieb
X. Shirley Liu

First Published February 7, 2008

LETTER

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

Graham R. Bignell
Thomas Santarius
Jessica C.M. Pole
Adam P. Butler
Janet Perry
Erin Pleasance Chris Greenman Andrew Menzies Sheila Taylor Sarah Edkins Peter Campbell Michael Quail Bob Plumb Lucy Matthews Kirsten McLay Paul A.W. Edwards
... [+11 authors] ...,
Jane Rogers
Richard Wooster
P. Andrew Futreal
Michael R. Stratton

First Published August 3, 2007

ARTICLE

Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes

Alvaro Rada-Iglesias
Stefan Enroth
Adam Ameur
Christoph M. Koch
Gayle K. Clelland
Patricia Respuela-Alonso Sarah Wilcox Oliver M. Dovey Peter D. Ellis
... [+4 authors] ...,
Cordelia F. Langford
Ian Dunham
Jan Komorowski
Claes Wadelius

First Published June 13, 2007

ARTICLE

The landscape of histone modifications across 1% of the human genome in five human cell lines

Christoph M. Koch
Robert M. Andrews
Paul Flicek
Shane C. Dillon
Ulaş Karaöz
Gayle K. Clelland Sarah Wilcox David M. Beare Joanna C. Fowler Phillippe Couttet Keith D. James Gregory C. Lefebvre Alexander W. Bruce Oliver M. Dovey Peter D. Ellis Pawandeep Dhami Cordelia F. Langford Zhiping Weng
... [+13 authors] ...,
Ewan Birney
Nigel P. Carter
David Vetrie
Ian Dunham

First Published June 13, 2007

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Your search for returned 20 results

Method

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

Corrigendum

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Research

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Research

C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency" > C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

Method

Estimation of rearrangement phylogeny for cancer genomes

Letter

Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level

LETTER

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

LETTER

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

ARTICLE

Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes

ARTICLE

The landscape of histone modifications across 1% of the human genome in five human cell lines

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