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Research

Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes

Mohamed Belhocine
Mathieu Simonin
José David Abad Flores
Agata Cieslak
Iris Manosalva
Lydie Pradel Charlotte Smith Eve-Lyne Mathieu Guillaume Charbonnier Joost H.A. Martens Hendrik G. Stunnenberg Muhammad Ahmad Maqbool Aneta Mikulasova Lisa J. Russell Daniel Rico
... [+10 authors] ...,
Denis Puthier
Pierre Ferrier
Vahid Asnafi
Salvatore Spicuglia

First Published June 23, 2021

Method

A plug and play microfluidic platform for standardized sensitive low-input chromatin immunoprecipitation

René A.M. Dirks
Peter C. Thomas
Haoyu Wu
Robert C. Jones
Hendrik G. Stunnenberg
Hendrik Marks

First Published March 11, 2021

Research

Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

Raquel Ordoñez
Marta Kulis
Nuria Russiñol
Vicente Chapaprieta
Arantxa Carrasco-Leon
Beatriz García-Torre Stella Charalampopoulou Guillem Clot Renée Beekman Cem Meydan Martí Duran-Ferrer Núria Verdaguer-Dot Roser Vilarrasa-Blasi Paula Soler-Vila Leire Garate Estíbaliz Miranda Edurne San José-Enériz Juan R. Rodriguez-Madoz Teresa Ezponda Rebeca Martínez-Turrilas Amaia Vilas-Zornoza David Lara-Astiaso Daphné Dupéré-Richer Joost H.A. Martens Halima El-Omri Ruba Y. Taha Maria J. Calasanz Bruno Paiva Jesus San Miguel Paul Flicek Ivo Gut Ari Melnick Constantine S. Mitsiades Jonathan D. Licht Elias Campo
... [+30 authors] ...,
Hendrik G. Stunnenberg
Xabier Agirre
Felipe Prosper
Jose I. Martin-Subero

First Published August 20, 2020

Research

The circular RNome of primary breast cancer

Marcel Smid
Saskia M. Wilting
Katharina Uhr
F. Germán Rodríguez-González
Vanja de Weerd
Wendy J.C. Prager-Van der Smissen Michelle van der Vlugt-Daane Anne van Galen Serena Nik-Zainal Adam Butler Sancha Martin Helen R. Davies Johan Staaf Marc J. van de Vijver Andrea L. Richardson Gaëten MacGrogan Roberto Salgado Gert G.G.M. van den Eynden Colin A. Purdie Alastair M. Thompson Carlos Caldas Paul N. Span Fred C.G.J. Sweep Peter T. Simpson Sunil R. Lakhani Steven Van Laere Christine Desmedt Angelo Paradiso Jorunn Eyfjord Annegien Broeks Anne Vincent-Salomon Andrew P. Futreal Stian Knappskog Tari King Alain Viari Anne-Lise Børresen-Dale Hendrik G. Stunnenberg
... [+32 authors] ...,
Mike Stratton
John A. Foekens
Anieta M. Sieuwerts
John W.M. Martens

First Published January 28, 2019

Research

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers

Xabier Agirre
Giancarlo Castellano
Marien Pascual
Simon Heath
Marta Kulis
Victor Segura Anke Bergmann Anna Esteve Angelika Merkel Emanuele Raineri Lidia Agueda Julie Blanc David Richardson Laura Clarke Avik Datta Nuria Russiñol Ana C. Queirós Renée Beekman Juan R. Rodríguez-Madoz Edurne San José-Enériz Fang Fang Norma C. Gutiérrez José M. García-Verdugo Michael I. Robson Eric C. Schirmer Elisabeth Guruceaga Joost H.A. Martens Marta Gut Maria J. Calasanz Paul Flicek Reiner Siebert Elías Campo Jesús F. San Miguel Ari Melnick
... [+29 authors] ...,
Hendrik G. Stunnenberg
Ivo G. Gut
Felipe Prosper
José I. Martín-Subero

First Published February 2, 2015

Method

Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk

Arie B. Brinkman
Hongcang Gu
Stefanie J.J. Bartels
Yingying Zhang
Filomena Matarese
Femke Simmer Hendrik Marks
... [+2 authors] ...,
Christoph Bock
Andreas Gnirke
Alexander Meissner
Hendrik G. Stunnenberg

First Published March 30, 2012

Research

Coactivation of GR and NFKB alters the repertoire of their binding sites and target genes

Nagesha A.S. Rao
Melysia T. McCalman
Panagiotis Moulos
Kees-Jan Francoijs
Aristotelis Chatziioannou
Fragiskos N. Kolisis
Michael N. Alexis
Dimitra J. Mitsiou
Hendrik G. Stunnenberg

First Published July 12, 2011

Research

Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesis

Ozren Bogdanović
Steven W. Long
Simon J. van Heeringen
Arie B. Brinkman
Jose Luis Gómez-Skarmeta
Hendrik G. Stunnenberg
Peter L. Jones
Gert Jan C. Veenstra

First Published June 2, 2011

Letter

High-resolution analysis of epigenetic changes associated with X inactivation

Hendrik Marks
Jennifer C. Chow
Sergei Denissov
Kees-Jan Françoijs
Neil Brockdorff
Edith Heard
Hendrik G. Stunnenberg

First Published July 6, 2009