Research
Long-read genome sequencing and variant reanalysis increase diagnostic yield in neurodevelopmental disorders
- First Published September 19, 2024
Resource
Allele-specific transcription factor binding across human brain regions offers mechanistic insight into eQTLs
- First Published August 16, 2024
Method
Probabilistic association of differentially expressed genes with cis-regulatory elements
- First Published April 17, 2024
Research
Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands
- First Published April 20, 2021
Resource
A genome-wide interactome of DNA-associated proteins in the human liver
- First Published October 11, 2017
Research
A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity
- First Published November 9, 2016
Method
An extended set of yeast-based functional assays accurately identifies human disease mutations
- First Published March 14, 2016
Research
Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites
- First Published October 20, 2015
Letter
Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes
- First Published January 12, 2010
Resource
Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome
- First Published October 2, 2009
Resource
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
- First Published June 23, 2009
Methods
A method for rapid, targeted CNV genotyping identifies rare variants associated with neurocognitive disease
- First Published June 8, 2009
Methods
Shifted Transversal Design smart-pooling for high coverage interactome mapping
- First Published May 15, 2009
PERSPECTIVE
Qualifying the relationship between sequence conservation and molecular function
- First Published February 1, 2008
ARTICLE
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome
- First Published June 13, 2007
ARTICLE
Distribution and intensity of constraint in mammalian genomic sequence
- First Published June 17, 2005
RESOURCE
Closing in on the C. elegans ORFeome by cloning TWINSCAN predictions
- First Published April 1, 2005
LETTER
New genes with roles in the C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones
- First Published February 1, 2005
PERSPECTIVE
ORFeome Cloning and Systems Biology: Standardized Mass Production of the Parts From the Parts-List
- First Published October 15, 2004
Insight/Outlook
Academia-Industry Collaboration: An Integral Element for Building “Omic” Resources
- First Published October 15, 2004
LETTER
C. elegans ORFeome Version 3.1: Increasing the Coverage of ORFeome Resources With Improved Gene Predictions
- First Published October 15, 2004
RESOURCE
Human ORFeome Version 1.1: A Platform for Reverse Proteomics
- First Published October 15, 2004
Methods
Annotation Transfer Between Genomes: Protein–Protein Interologs and Protein–DNA Regulogs
- First Published June 1, 2004
Methods
Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human
- First Published April 1, 2004
LETTER
Characterization of Evolutionary Rates and Constraints in Three Mammalian Genomes
- First Published April 1, 2004
LETTER
Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes
- First Published May 1, 2003
METHODS
LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA
- First Published March 12, 2003
METHODS
Identification of Potential Interaction Networks Using Sequence-Based Searches for Conserved Protein-Protein Interactions or “Interologs”
- First Published December 1, 2001
METHODS
A Genetic Strategy to Eliminate Self-Activator Baits Prior to High-Throughput Yeast Two-Hybrid Screens
- First Published November 1, 1999