Research
Transcriptomic and proteomic effects of gene deletion are not evolutionarily conserved
- First Published February 18, 2025
Research
Long-read genome sequencing and variant reanalysis increase diagnostic yield in neurodevelopmental disorders
- First Published September 19, 2024
Resource
Allele-specific transcription factor binding across human brain regions offers mechanistic insight into eQTLs
- First Published August 16, 2024
Method
Probabilistic association of differentially expressed genes with cis-regulatory elements
- First Published April 17, 2024
Research
Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands
- First Published April 20, 2021
Resource
A genome-wide interactome of DNA-associated proteins in the human liver
- First Published October 11, 2017
Research
A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity
- First Published November 9, 2016
Research
Nascent RNA folding mitigates transcription-associated mutagenesis
- First Published October 30, 2015
Research
Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites
- First Published October 20, 2015
Letter
Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes
- First Published January 12, 2010
Methods
A method for rapid, targeted CNV genotyping identifies rare variants associated with neurocognitive disease
- First Published June 8, 2009
PERSPECTIVE
Qualifying the relationship between sequence conservation and molecular function
- First Published February 1, 2008
LETTER
Evolutionary dynamics of nematode operons: Easy come, slow go
- First Published January 24, 2008
ARTICLE
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome
- First Published June 13, 2007
LETTER
Comparative genomic analysis identifies an evolutionary shift of vomeronasal receptor gene repertoires in the vertebrate transition from water to land
- First Published January 8, 2007
LETTER
Evolution of the complementary sex-determination gene of honey bees: Balancing selection and trans-species polymorphisms
- First Published October 25, 2006
ARTICLE
Distribution and intensity of constraint in mammalian genomic sequence
- First Published June 17, 2005
LETTER
Testing the Chromosomal Speciation Hypothesis for Humans and Chimpanzees
- First Published May 3, 2004
Methods
Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human
- First Published April 1, 2004
LETTER
Characterization of Evolutionary Rates and Constraints in Three Mammalian Genomes
- First Published April 1, 2004
LETTER
Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes
- First Published May 1, 2003
METHODS
LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA
- First Published March 12, 2003