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Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

  • Myungjin Jo
  • Ah Young Chung
  • Nozomu Yachie
  • Minchul Seo
  • Hyejin Jeon
  • Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
  • ... [+4 authors] ...,
  • Marc Vidal
  • Hae Chul Park
  • Frederick P. Roth
  • Kyoungho Suk
  • First Published June 8, 2017
Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

  • Song Sun
  • Fan Yang
  • Guihong Tan
  • Michael Costanzo
  • Rose Oughtred
  • Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
  • ... [+10 authors] ...,
  • Brenda J. Andrews
  • Charles Boone
  • Kara Dolinski
  • Frederick P. Roth
  • First Published March 14, 2016
Research

TCF7L2 expression define its role as a key regulator of glucose metabolism" > Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism

  • Daniel Savic
  • Honggang Ye
  • Ivy Aneas
  • Soo-Young Park
  • Graeme I. Bell
  • Marcelo A. Nobrega
  • First Published June 14, 2011
Method

Genome-wide identification of conserved regulatory function in diverged sequences

  • Leila Taher
  • David M. McGaughey
  • Samantha Maragh
  • Ivy Aneas
  • Seneca L. Bessling
  • Webb Miller
  • Marcelo A. Nobrega
  • Andrew S. McCallion
  • Ivan Ovcharenko
  • First Published May 31, 2011
Research

MYC enhancer" > An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer

  • Nora F. Wasserman
  • Ivy Aneas
  • Marcelo A. Nobrega
  • First Published July 13, 2010
Research

Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers

  • Valer Gotea
  • Axel Visel
  • John M. Westlund
  • Marcelo A. Nobrega
  • Len A. Pennacchio
  • Ivan Ovcharenko
  • First Published April 2, 2010
Methods

Genome-wide discovery of human heart enhancers

  • Leelavati Narlikar
  • Noboru J. Sakabe
  • Alexander A. Blanski
  • Fabio E. Arimura
  • John M. Westlund
  • Marcelo A. Nobrega
  • Ivan Ovcharenko
  • First Published January 14, 2010
Resource

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

  • Kourosh Salehi-Ashtiani
  • Chenwei Lin
  • Tong Hao
  • Yun Shen
  • David Szeto
  • Xinping Yang Lila Ghamsari HanJoo Lee Changyu Fan Ryan R. Murray Stuart Milstein Nenad Svrzikapa
  • ... [+7 authors] ...,
  • Michael E. Cusick
  • Frederick P. Roth
  • David E. Hill
  • Marc Vidal
  • First Published October 2, 2009
Methods

Quantitative phenotyping via deep barcode sequencing

  • Andrew M. Smith
  • Lawrence E. Heisler
  • Joseph Mellor
  • Fiona Kaper
  • Michael J. Thompson
  • Mark Chee
  • Frederick P. Roth
  • Guri Giaever
  • Corey Nislow
  • First Published July 21, 2009
Methods

Predicting tissue-specific enhancers in the human genome

  • Len A. Pennacchio
  • Gabriela G. Loots
  • Marcelo A. Nobrega
  • Ivan Ovcharenko
  • First Published January 8, 2007
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