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Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

Myungjin Jo
Ah Young Chung
Nozomu Yachie
Minchul Seo
Hyejin Jeon
Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
... [+4 authors] ...,
Marc Vidal
Hae Chul Park
Frederick P. Roth
Kyoungho Suk

First Published June 8, 2017

Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

Song Sun
Fan Yang
Guihong Tan
Michael Costanzo
Rose Oughtred
Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
... [+10 authors] ...,
Brenda J. Andrews
Charles Boone
Kara Dolinski
Frederick P. Roth

First Published March 14, 2016

Resource

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

Kourosh Salehi-Ashtiani
Chenwei Lin
Tong Hao
Yun Shen
David Szeto
Xinping Yang Lila Ghamsari HanJoo Lee Changyu Fan Ryan R. Murray Stuart Milstein Nenad Svrzikapa
... [+7 authors] ...,
Michael E. Cusick
Frederick P. Roth
David E. Hill
Marc Vidal

First Published October 2, 2009

Methods

Quantitative phenotyping via deep barcode sequencing

Andrew M. Smith
Lawrence E. Heisler
Joseph Mellor
Fiona Kaper
Michael J. Thompson
Mark Chee
Frederick P. Roth
Guri Giaever
Corey Nislow

First Published July 21, 2009

Methods

Predicting Protein Complex Membership Using Probabilistic Network Reliability

Saurabh Asthana
Oliver D. King
Francis D. Gibbons
Frederick P. Roth

First Published May 12, 2004

METHODS

Predicting Gene Function From Patterns of Annotation

Oliver D. King
Rebecca E. Foulger
Selina S. Dwight
James V. White
Frederick P. Roth

First Published April 14, 2003

METHODS

Judging the Quality of Gene Expression-Based Clustering Methods Using Gene Annotation

Francis D. Gibbons
Frederick P. Roth

First Published October 1, 2002

INSIGHT/OUTLOOK

Bringing Out the Best Features of Expression Data

Frederick P. Roth

First Published November 1, 2001