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Perspective

The Topological Regulatory Logic of noncoding RNA–mediated gene expression

  • First Published June 17, 2026
Method

A deconvolution framework that uses single-cell sequencing plus a small benchmark data set for accurate analysis of cell type ratios in complex tissue samples

  • First Published November 25, 2024
Method

Accelerated somatic mutation calling for whole-genome and whole-exome sequencing data from heterogenous tumor samples

  • First Published April 8, 2024
Method

Accurate sequencing of DNA motifs able to form alternative (non-B) structures

  • First Published July 11, 2023
Research

Selection and thermostability suggest G-quadruplexes are novel functional elements of the human genome

  • First Published June 29, 2021
Method

A pedigree-based prediction model identifies carriers of deleterious de novo mutations in families with Li-Fraumeni syndrome

  • First Published August 18, 2020
Resource

A limited set of transcriptional programs define major cell types

  • First Published July 29, 2020
Resource

Dynamics of microRNA expression during mouse prenatal development

  • First Published October 23, 2019
Research

Long-read sequencing technology indicates genome-wide effects of non-B DNA on polymerization speed and error rate

  • First Published November 6, 2018
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