Method
A deconvolution framework that uses single-cell sequencing plus a small benchmark data set for accurate analysis of cell type ratios in complex tissue samples
- First Published November 25, 2024
Method
Accelerated somatic mutation calling for whole-genome and whole-exome sequencing data from heterogenous tumor samples
- First Published April 8, 2024
Method
Accurate sequencing of DNA motifs able to form alternative (non-B) structures
- First Published July 11, 2023
Method
Analyzing rare mutations in metagenomes assembled using long and accurate reads
- First Published November 23, 2022
Method
Fast and accurate mapping of long reads to complete genome assemblies with VerityMap
- First Published November 15, 2022
Method
Variations in antibody repertoires correlate with vaccine responses
- First Published March 31, 2022
Research
Selection and thermostability suggest G-quadruplexes are novel functional elements of the human genome
- First Published June 29, 2021
Research
V(DD)J recombination is an important and evolutionarily conserved mechanism for generating antibodies with unusually long CDR3s
- First Published September 18, 2020
Method
A pedigree-based prediction model identifies carriers of deleterious de novo mutations in families with Li-Fraumeni syndrome
- First Published August 18, 2020