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Method

Complex hierarchical structures in single-cell genomics data unveiled by deep hyperbolic manifold learning

Tian Tian
Cheng Zhong
Xiang Lin
Zhi Wei
Hakon Hakonarson

First Published February 27, 2023

Method

A model-based constrained deep learning clustering approach for spatially resolved single-cell data

Xiang Lin
Le Gao
Nathan Whitener
Ashley Ahmed
Zhi Wei

First Published October 5, 2022

Research

Toxoplasma gondii and identifies emerging copy number variants in sexual recombinants" > Third-generation sequencing revises the molecular karyotype for Toxoplasma gondii and identifies emerging copy number variants in sexual recombinants

Jing Xia
Aarthi Venkat
Rachel E. Bainbridge
Michael L. Reese
Karine G. Le Roch
Ferhat Ay
Jon P. Boyle

First Published April 27, 2021

Method

Multi–cell type gene coexpression network analysis reveals coordinated interferon response and cross–cell type correlations in systemic lupus erythematosus

Bharat Panwar
Benjamin J. Schmiedel
Shu Liang
Brandie White
Enrique Rodriguez
Kenneth Kalunian Andrew J. McKnight
... [+2 authors] ...,
Rachel Soloff
Gregory Seumois
Pandurangan Vijayanand
Ferhat Ay

First Published March 5, 2021

Research

Replication timing networks reveal a link between transcription regulatory circuits and replication timing control

Juan Carlos Rivera-Mulia
Sebo Kim
Haitham Gabr
Abhijit Chakraborty
Ferhat Ay
Tamer Kahveci
David M. Gilbert

First Published August 21, 2019

Method

Profiling the long noncoding RNA interaction network in the regulatory elements of target genes by chromatin in situ reverse transcription sequencing

Shilin Zhang
Yichen Wang
Lin Jia
Xue Wen
Zhonghua Du
Cong Wang Yajing Hao Dehai Yu Lei Zhou Naifei Chen Jingcheng Chen Huiling Chen Hui Zhang Ilkay Celik Günhan Gülsoy Jianjun Luo Baoming Qin Xueling Cui Zhonghui Liu Songling Zhang Miguel A. Esteban Ferhat Ay Wei Xu Runsheng Chen
... [+19 authors] ...,
Wei Li
Andrew R. Hoffman
Ji-Fan Hu
Jiuwei Cui

First Published July 17, 2019

Research

Comprehensive identification and analysis of human accelerated regulatory DNA

Rachel M. Gittelman
Enna Hun
Ferhat Ay
Jennifer Madeoy
Len Pennacchio
William S. Noble
R. David Hawkins
Joshua M. Akey

First Published June 23, 2015

Research

Topologically associating domains and their long-range contacts are established during early G1 coincident with the establishment of the replication-timing program

Vishnu Dileep
Ferhat Ay
Jiao Sima
Daniel L. Vera
William S. Noble
David M. Gilbert

First Published May 20, 2015

Method

Joint annotation of chromatin state and chromatin conformation reveals relationships among domain types and identifies domains of cell-type-specific expression

Maxwell W. Libbrecht
Ferhat Ay
Michael M. Hoffman
David M. Gilbert
Jeffrey A. Bilmes
William Stafford Noble

First Published February 12, 2015

Research

P. falciparum genome during the erythrocytic cycle reveals a strong connection between genome architecture and gene expression" > Three-dimensional modeling of the P. falciparum genome during the erythrocytic cycle reveals a strong connection between genome architecture and gene expression

Ferhat Ay
Evelien M. Bunnik
Nelle Varoquaux
Sebastiaan M. Bol
Jacques Prudhomme
Jean-Philippe Vert
William Stafford Noble
Karine G. Le Roch

First Published March 26, 2014

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