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Research

Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation

  • First Published December 5, 2024
Research

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma

  • First Published June 27, 2019
Method

TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data

  • First Published July 24, 2014
Method

Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm

  • First Published June 26, 2013
Method

Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

  • First Published June 26, 2013
Resource

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

  • First Published September 5, 2012
Research

Understanding transcriptional regulation by integrative analysis of transcription factor binding data

  • First Published September 5, 2012
Method

Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer

  • First Published May 25, 2012
Research

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

  • First Published November 16, 2011
Resource

Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

  • First Published July 12, 2011
Research

Extensive relationship between antisense transcription and alternative splicing in the human genome

  • First Published June 30, 2011
Method

Efficient storage of high throughput DNA sequencing data using reference-based compression

  • First Published January 18, 2011
Research

Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence" > Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence

  • First Published December 22, 2010
Method

High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells

  • First Published November 24, 2010
Research

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver

  • First Published June 15, 2010
Research

The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance

  • First Published April 29, 2010
RESOURCE

An effective model for natural selection in promoters

  • First Published March 1, 2010
Methods

A new strategy for genome assembly using short sequence reads and reduced representation libraries

  • First Published February 1, 2010
Resource

The completion of the Mammalian Gene Collection (MGC)

  • First Published September 18, 2009
Methods

Next-generation tag sequencing for cancer gene expression profiling

  • First Published June 18, 2009
Resource

Circos: An information aesthetic for comparative genomics

  • First Published June 18, 2009
Resource

The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes

  • First Published June 4, 2009
RESOURCE

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

  • First Published November 24, 2008
Methods

Enredo and Pecan: Genome-wide mammalian consistency-based multiple alignment with paralogs

  • First Published October 10, 2008
LETTER

In-depth characterization of the microRNA transcriptome in a leukemia progression model

  • First Published October 10, 2008
Methods

Genome-wide nucleotide-level mammalian ancestor reconstruction

  • First Published October 10, 2008
LETTER

Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding

  • First Published September 11, 2008
Methods

Confounding between recombination and selection, and the Ped/Pop method for detecting selection

  • First Published July 10, 2008
RESOURCE

An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)

  • First Published June 24, 2008
RESOURCE

Velvet: Algorithms for de novo short read assembly using de Bruijn graphs

  • First Published March 18, 2008
Methods

Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

  • First Published February 19, 2008
LETTER

Caenorhabditis elegans operons" > Identification and analysis of internal promoters in Caenorhabditis elegans operons

  • First Published August 21, 2007
ARTICLE

The landscape of histone modifications across 1% of the human genome in five human cell lines

  • First Published June 13, 2007
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
Methods

Identification of novel peptide hormones in the human proteome by hidden Markov model screening

  • First Published February 6, 2007
Methods

Large-scale production of SAGE libraries from microdissected tissues, flow-sorted cells, and cell lines

  • First Published November 29, 2006
Methods

Physical map-assisted whole-genome shotgun sequence assemblies

  • First Published June 1, 2006
RESOURCE

Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling" > Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling

  • First Published May 3, 2006
LETTER

Identification by full-coverage array CGH of human DNA copy number increases relative to chimpanzee and gorilla

  • First Published December 19, 2005
Methods

Simple, robust methods for high-throughput nanoliter-scale DNA sequencing

  • First Published September 16, 2005
ARTICLE

C. elegans daf-2 mutants using serial analysis of gene expression" > Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression

  • First Published April 18, 2005
Chicken Special/Resources

Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags

  • First Published December 8, 2004
Methods

Systematic Recovery and Analysis of Full-ORF Human cDNA Clones

  • First Published October 15, 2004
ENSEMBL Special

The Ensembl Core Software Libraries

  • First Published May 3, 2004
ENSEMBL Special

GeneWise and Genomewise

  • First Published May 3, 2004
ENSEMBL Special

Sockeye: A 3D Environment for Comparative Genomics

  • First Published May 3, 2004
ENSEMBL Special

An Overview of Ensembl

  • First Published April 12, 2004
LETTER

Comparison of Human Chromosome 21 Conserved Nongenic Sequences (CNGs) With the Mouse and Dog Genomes Shows That Their Selective Constraint Is Independent of Their Genic Environment

  • First Published April 12, 2004
RESOURCE

Development and Application of a Salmonid EST Database and cDNA Microarray: Data Mining and Interspecific Hybridization Characteristics

  • First Published February 12, 2004
RESOURCE

EnsMart: A Generic System for Fast and Flexible Access to Biological Data

  • First Published January 5, 2004
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