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Your search for returned 59 results

Research

A quantitative framework for characterizing the evolutionary history of mammalian gene expression

Jenny Chen
Ross Swofford
Jeremy Johnson
Beryl B. Cummings
Noga Rogel
Kerstin Lindblad-Toh
Wilfried Haerty
Federica di Palma
Aviv Regev

First Published December 14, 2018

Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

Myungjin Jo
Ah Young Chung
Nozomu Yachie
Minchul Seo
Hyejin Jeon
Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
... [+4 authors] ...,
Marc Vidal
Hae Chul Park
Frederick P. Roth
Kyoungho Suk

First Published June 8, 2017

Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

Song Sun
Fan Yang
Guihong Tan
Michael Costanzo
Rose Oughtred
Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
... [+10 authors] ...,
Brenda J. Andrews
Charles Boone
Kara Dolinski
Frederick P. Roth

First Published March 14, 2016

Research

Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background

Ingegerd Elvers
Jason Turner-Maier
Ross Swofford
Michele Koltookian
Jeremy Johnson
Chip Stewart Cheng-Zhong Zhang Steven E. Schumacher Rameen Beroukhim Mara Rosenberg Rachael Thomas Evan Mauceli Gad Getz Federica Di Palma
... [+9 authors] ...,
Jaime F. Modiano
Matthew Breen
Kerstin Lindblad-Toh
Jessica Alföldi

First Published September 16, 2015

Perspective

Comparative genomics as a tool to understand evolution and disease

Jessica Alföldi
Kerstin Lindblad-Toh

First Published July 1, 2013

Resource

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

Jie Wang
Jiali Zhuang
Sowmya Iyer
XinYing Lin
Troy W. Whitfield
Melissa C. Greven Brian G. Pierce Xianjun Dong Anshul Kundaje Yong Cheng Oliver J. Rando Ewan Birney
... [+7 authors] ...,
Richard M. Myers
William S. Noble
Michael Snyder
Zhiping Weng

First Published September 5, 2012

Research

Understanding transcriptional regulation by integrative analysis of transcription factor binding data

Chao Cheng
Roger Alexander
Renqiang Min
Jing Leng
Kevin Y. Yip
Joel Rozowsky Koon-Kiu Yan Xianjun Dong Sarah Djebali Yijun Ruan Carrie A. Davis Piero Carninci Timo Lassman Thomas R. Gingeras Roderic Guigó
... [+10 authors] ...,
Ewan Birney
Zhiping Weng
Michael Snyder
Mark Gerstein

First Published September 5, 2012

Research

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

Bum-Kyu Lee
Akshay A. Bhinge
Anna Battenhouse
Ryan M. McDaniell
Zheng Liu
Lingyun Song Yunyun Ni Ewan Birney
... [+3 authors] ...,
Jason D. Lieb
Terrence S. Furey
Gregory E. Crawford
Vishwanath R. Iyer

First Published November 16, 2011

Research

PRDM9 coincides with stabilization of the recombination landscape in the dog genome" > Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome

Erik Axelsson
Matthew T. Webster
Abhirami Ratnakumar
Chris P. Ponting
Kerstin Lindblad-Toh

First Published October 17, 2011

Resource

Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

Lingyun Song
Zhancheng Zhang
Linda L. Grasfeder
Alan P. Boyle
Paul G. Giresi
Bum-Kyu Lee Nathan C. Sheffield Stefan Gräf Mikael Huss Damian Keefe Zheng Liu Darin London Ryan M. McDaniell Yoichiro Shibata Kimberly A. Showers Jeremy M. Simon Teresa Vales Tianyuan Wang Deborah Winter Zhuzhu Zhang Neil D. Clarke Ewan Birney
... [+17 authors] ...,
Vishwanath R. Iyer
Gregory E. Crawford
Jason D. Lieb
Terrence S. Furey

First Published July 12, 2011

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