Search | Genome Research

Understanding transcriptional regulation by integrative analysis of transcription factor binding data

Chao Cheng
Roger Alexander
Renqiang Min
Jing Leng
Kevin Y. Yip
Joel Rozowsky Koon-Kiu Yan Xianjun Dong Sarah Djebali Yijun Ruan Carrie A. Davis Piero Carninci Timo Lassman Thomas R. Gingeras Roderic Guigó
... [+10 authors] ...,
Ewan Birney
Zhiping Weng
Michael Snyder
Mark Gerstein

First Published September 5, 2012

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

Jie Wang
Jiali Zhuang
Sowmya Iyer
XinYing Lin
Troy W. Whitfield
Melissa C. Greven Brian G. Pierce Xianjun Dong Anshul Kundaje Yong Cheng Oliver J. Rando Ewan Birney
... [+7 authors] ...,
Richard M. Myers
William S. Noble
Michael Snyder
Zhiping Weng

First Published September 5, 2012

Translating cancer ‘omics’ to improved outcomes

Emily A. Vucic
Kelsie L. Thu
Keith Robison
Leszek A. Rybaczyk
Raj Chari
Carlos E. Alvarez
Wan L. Lam

First Published February 1, 2012

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

Bum-Kyu Lee
Akshay A. Bhinge
Anna Battenhouse
Ryan M. McDaniell
Zheng Liu
Lingyun Song Yunyun Ni Ewan Birney
... [+3 authors] ...,
Jason D. Lieb
Terrence S. Furey
Gregory E. Crawford
Vishwanath R. Iyer

First Published November 16, 2011

Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

Lingyun Song
Zhancheng Zhang
Linda L. Grasfeder
Alan P. Boyle
Paul G. Giresi
Bum-Kyu Lee Nathan C. Sheffield Stefan Gräf Mikael Huss Damian Keefe Zheng Liu Darin London Ryan M. McDaniell Yoichiro Shibata Kimberly A. Showers Jeremy M. Simon Teresa Vales Tianyuan Wang Deborah Winter Zhuzhu Zhang Neil D. Clarke Ewan Birney
... [+17 authors] ...,
Vishwanath R. Iyer
Gregory E. Crawford
Jason D. Lieb
Terrence S. Furey

First Published July 12, 2011

Efficient storage of high throughput DNA sequencing data using reference-based compression

Markus Hsi-Yang Fritz
Rasko Leinonen
Guy Cochrane
Ewan Birney

First Published January 18, 2011

High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells

Alan P. Boyle
Lingyun Song
Bum-Kyu Lee
Darin London
Damian Keefe
Ewan Birney
Vishwanath R. Iyer
Gregory E. Crawford
Terrence S. Furey

First Published November 24, 2010

The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance

Santosh S. Atanur
İnanç Birol
Victor Guryev
Martin Hirst
Oliver Hummel
Catherine Morrissey Jacques Behmoaras Xose M. Fernandez-Suarez Michelle D. Johnson William M. McLaren Giannino Patone Enrico Petretto Charles Plessy Kathleen S. Rockland Charles Rockland Kathrin Saar Yongjun Zhao Piero Carninci Paul Flicek Ted Kurtz Edwin Cuppen Michal Pravenec
... [+17 authors] ...,
Norbert Hubner
Steven J.M. Jones
Ewan Birney
Timothy J. Aitman

First Published April 29, 2010

An effective model for natural selection in promoters

Michael M. Hoffman
Ewan Birney

First Published March 1, 2010

A new strategy for genome assembly using short sequence reads and reduced representation libraries

Andrew L. Young
Hatice Ozel Abaan
Daniel Zerbino
James C. Mullikin
Ewan Birney
Elliott H. Margulies

First Published February 1, 2010

The completion of the Mammalian Gene Collection (MGC)

Gary Temple
Daniela S. Gerhard
Rebekah Rasooly
Elise A. Feingold
Peter J. Good
Cristen Robinson Allison Mandich Jeffrey G. Derge Jeanne Lewis Debonny Shoaf Francis S. Collins Wonhee Jang Lukas Wagner Carolyn M. Shenmen Leonie Misquitta Carl F. Schaefer Kenneth H. Buetow Tom I. Bonner Linda Yankie Ming Ward Lon Phan Alex Astashyn Garth Brown Catherine Farrell Jennifer Hart Melissa Landrum Bonnie L. Maidak Michael Murphy Terence Murphy Bhanu Rajput Lillian Riddick David Webb Janet Weber Wendy Wu Kim D. Pruitt Donna Maglott Adam Siepel Brona Brejova Mark Diekhans Rachel Harte Robert Baertsch Jim Kent David Haussler Michael Brent Laura Langton Charles L.G. Comstock Michael Stevens Chaochun Wei Marijke J. van Baren Kourosh Salehi-Ashtiani Ryan R. Murray Lila Ghamsari Elizabeth Mello Chenwei Lin Christa Pennacchio Kirsten Schreiber Nicole Shapiro Amber Marsh Elizabeth Pardes Troy Moore Anita Lebeau Mike Muratet Blake Simmons David Kloske Stephanie Sieja James Hudson Praveen Sethupathy Michael Brownstein Narayan Bhat Joseph Lazar Howard Jacob Chris E. Gruber Mark R. Smith John McPherson Angela M. Garcia Preethi H. Gunaratne Jiaqian Wu Donna Muzny Richard A. Gibbs Alice C. Young Gerard G. Bouffard Robert W. Blakesley Jim Mullikin Eric D. Green Mark C. Dickson Alex C. Rodriguez Jane Grimwood Jeremy Schmutz Richard M. Myers Martin Hirst Thomas Zeng Kane Tse Michelle Moksa Merinda Deng Kevin Ma Diana Mah Johnson Pang Greg Taylor Eric Chuah Athena Deng Keith Fichter Anne Go Stephanie Lee Jing Wang Malachi Griffith Ryan Morin Richard A. Moore Michael Mayo Sarah Munro Susan Wagner Steven J.M. Jones Robert A. Holt Marco A. Marra Sun Lu Shuwei Yang James Hartigan Marcus Graf Ralf Wagner Stanley Letovksy Jacqueline C. Pulido Keith Robison Dominic Esposito James Hartley
... [+118 authors] ...,
Vanessa E. Wall
Ralph F. Hopkins
Osamu Ohara
Stefan Wiemann

First Published September 18, 2009

The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes

Kim D. Pruitt
Jennifer Harrow
Rachel A. Harte
Craig Wallin
Mark Diekhans
Donna R. Maglott Steve Searle Catherine M. Farrell Jane E. Loveland Barbara J. Ruef Elizabeth Hart Marie-Marthe Suner Melissa J. Landrum Bronwen Aken Sarah Ayling Robert Baertsch Julio Fernandez-Banet Joshua L. Cherry Val Curwen Michael DiCuccio Manolis Kellis Jennifer Lee Michael F. Lin Michael Schuster Andrew Shkeda Clara Amid Garth Brown Oksana Dukhanina Adam Frankish Jennifer Hart Bonnie L. Maidak Jonathan Mudge Michael R. Murphy Terence Murphy Jeena Rajan Bhanu Rajput Lillian D. Riddick Catherine Snow Charles Steward David Webb Janet A. Weber Laurens Wilming Wenyu Wu Ewan Birney David Haussler
... [+40 authors] ...,
Tim Hubbard
James Ostell
Richard Durbin
David Lipman

First Published June 4, 2009

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

Albert J. Vilella
Jessica Severin
Abel Ureta-Vidal
Li Heng
Richard Durbin
Ewan Birney

First Published November 24, 2008

Enredo and Pecan: Genome-wide mammalian consistency-based multiple alignment with paralogs

Benedict Paten
Javier Herrero
Kathryn Beal
Stephen Fitzgerald
Ewan Birney

First Published October 10, 2008

Genome-wide nucleotide-level mammalian ancestor reconstruction

Benedict Paten
Javier Herrero
Stephen Fitzgerald
Kathryn Beal
Paul Flicek
Ian Holmes
Ewan Birney

First Published October 10, 2008

Confounding between recombination and selection, and the Ped/Pop method for detecting selection

Paul F. O’Reilly
Ewan Birney
David J. Balding

First Published July 10, 2008

An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)

Vardhman K. Rakyan
Thomas A. Down
Natalie P. Thorne
Paul Flicek
Eugene Kulesha
Stefan Gräf Eleni M. Tomazou Liselotte Bäckdahl Nathan Johnson Marlis Herberth Kevin L. Howe David K. Jackson Marcos M. Miretti Heike Fiegler John C. Marioni Ewan Birney
... [+11 authors] ...,
Tim J.P. Hubbard
Nigel P. Carter
Simon Tavaré
Stephan Beck

First Published June 24, 2008

Velvet: Algorithms for de novo short read assembly using de Bruijn graphs

Daniel R. Zerbino
Ewan Birney

First Published March 18, 2008

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

Elliott H. Margulies
Gregory M. Cooper
George Asimenos
Daryl J. Thomas
Colin N. Dewey
Adam Siepel Ewan Birney Damian Keefe Ariel S. Schwartz Minmei Hou James Taylor Sergey Nikolaev Juan I. Montoya-Burgos Ari Löytynoja Simon Whelan Fabio Pardi Tim Massingham James B. Brown Peter Bickel Ian Holmes James C. Mullikin Abel Ureta-Vidal Benedict Paten Eric A. Stone Kate R. Rosenbloom W. James Kent Gerard G. Bouffard Xiaobin Guan Nancy F. Hansen Jacquelyn R. Idol Valerie V.B. Maduro Baishali Maskeri Jennifer C. McDowell Morgan Park Pamela J. Thomas Alice C. Young Robert W. Blakesley Donna M. Muzny Erica Sodergren David A. Wheeler Kim C. Worley Huaiyang Jiang George M. Weinstock Richard A. Gibbs Tina Graves Robert Fulton Elaine R. Mardis Richard K. Wilson Michele Clamp James Cuff Sante Gnerre David B. Jaffe Jean L. Chang Kerstin Lindblad-Toh Eric S. Lander Angie Hinrichs Heather Trumbower Hiram Clawson Ann Zweig Robert M. Kuhn Galt Barber Rachel Harte Donna Karolchik Matthew A. Field Richard A. Moore Carrie A. Matthewson Jacqueline E. Schein Marco A. Marra Stylianos E. Antonarakis Serafim Batzoglou Nick Goldman Ross Hardison David Haussler
... [+68 authors] ...,
Webb Miller
Lior Pachter
Eric D. Green
Arend Sidow

First Published June 13, 2007

The landscape of histone modifications across 1% of the human genome in five human cell lines

Christoph M. Koch
Robert M. Andrews
Paul Flicek
Shane C. Dillon
Ulaş Karaöz
Gayle K. Clelland Sarah Wilcox David M. Beare Joanna C. Fowler Phillippe Couttet Keith D. James Gregory C. Lefebvre Alexander W. Bruce Oliver M. Dovey Peter D. Ellis Pawandeep Dhami Cordelia F. Langford Zhiping Weng
... [+13 authors] ...,
Ewan Birney
Nigel P. Carter
David Vetrie
Ian Dunham

First Published June 13, 2007

Identification of novel peptide hormones in the human proteome by hidden Markov model screening

Olivier Mirabeau
Emerald Perlas
Cinzia Severini
Enrica Audero
Olivier Gascuel
Roberta Possenti
Ewan Birney
Nadia Rosenthal
Cornelius Gross

First Published February 6, 2007

Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags

Simon J. Hubbard
Darren V. Grafham
Kevin J. Beattie
Ian M. Overton
Stuart R. McLaren
Michael D.R. Croning Paul E. Boardman James K. Bonfield Joan Burnside Robert M. Davies Elizabeth R. Farrell Matthew D. Francis Sam Griffiths-Jones Sean J. Humphray Christopher Hyland Carol E. Scott Haizhou Tang Ruth G. Taylor Cheryll Tickle
... [+14 authors] ...,
William R.A. Brown
Ewan Birney
Jane Rogers
Stuart A. Wilson

First Published December 8, 2004

The Ensembl Core Software Libraries

Arne Stabenau
Graham McVicker
Craig Melsopp
Glenn Proctor
Michele Clamp
Ewan Birney

First Published May 3, 2004

Sockeye: A 3D Environment for Comparative Genomics

Stephen B. Montgomery
Tamara Astakhova
Mikhail Bilenky
Ewan Birney
Tony Fu
Maik Hassel Craig Melsopp Marcin Rak
... [+3 authors] ...,
A. Gordon Robertson
Monica Sleumer
Asim S. Siddiqui
Steven J.M. Jones

First Published May 3, 2004

GeneWise and Genomewise

Ewan Birney
Michele Clamp
Richard Durbin

First Published May 3, 2004

An Overview of Ensembl

Ewan Birney
T. Daniel Andrews
Paul Bevan
Mario Caccamo
Yuan Chen
Laura Clarke Guy Coates James Cuff Val Curwen Tim Cutts Thomas Down Eduardo Eyras Xose M. Fernandez-Suarez Paul Gane Brian Gibbins James Gilbert Martin Hammond Hans-Rudolf Hotz Vivek Iyer Kerstin Jekosch Andreas Kahari Arek Kasprzyk Damian Keefe Stephen Keenan Heikki Lehvaslaiho Graham McVicker Craig Melsopp Patrick Meidl Emmanuel Mongin Roger Pettett Simon Potter Glenn Proctor Mark Rae Steve Searle Guy Slater Damian Smedley James Smith Will Spooner Arne Stabenau James Stalker Roy Storey Abel Ureta-Vidal K. Cara Woodwark Graham Cameron
... [+39 authors] ...,
Richard Durbin
Anthony Cox
Tim Hubbard
Michele Clamp

First Published April 12, 2004

Comparison of Human Chromosome 21 Conserved Nongenic Sequences (CNGs) With the Mouse and Dog Genomes Shows That Their Selective Constraint Is Independent of Their Genic Environment

Emmanouil T. Dermitzakis
Ewen Kirkness
Scott Schwarz
Ewan Birney
Alexandre Reymond
Stylianos E. Antonarakis

First Published April 12, 2004

EnsMart: A Generic System for Fast and Flexible Access to Biological Data

Arek Kasprzyk
Damian Keefe
Damian Smedley
Darin London
William Spooner
Craig Melsopp
... [+1 authors] ...,
Martin Hammond
Philippe Rocca-Serra
Tony Cox
Ewan Birney

First Published January 5, 2004

cis-Regulatory Motifs Using Functional Networks" > Discovering Novel cis-Regulatory Motifs Using Functional Networks

Laurence M. Ettwiller
Johan Rung
Ewan Birney

First Published May 1, 2003

The Bioperl Toolkit: Perl Modules for the Life Sciences

Jason E. Stajich
David Block
Kris Boulez
Steven E. Brenner
Stephen A. Chervitz
Chris Dagdigian Georg Fuellen James G.R. Gilbert Ian Korf Hilmar Lapp Heikki Lehväslaiho Chad Matsalla Chris J. Mungall Brian I. Osborne Matthew R. Pocock Peter Schattner Martin Senger
... [+12 authors] ...,
Lincoln D. Stein
Elia Stupka
Mark D. Wilkinson
Ewan Birney

First Published October 1, 2002

GeneWise in the Drosophila Annotation Experiment" > Using `GeneWise` in the Drosophila Annotation Experiment

Ewan Birney
Richard Durbin

First Published April 1, 2000

Comparative Analysis of Noncoding Regions of 77 Orthologous Mouse and Human Gene Pairs

Niclas Jareborg
Ewan Birney
Richard Durbin

First Published September 1, 1999

Mycobacterium leprae Genome" > Multiplex Sequencing of 1.5 Mb of the Mycobacterium leprae Genome

Douglas R. Smith
Peter Richterich
Marc Rubenfield
Philip W. Rice
Carol Butler
Hong-Mei Lee Susan Kirst Kristin Gundersen Kari Abendschan Qinxue Xu Maria Chung Craig Deloughery Tyler Aldredge James Maher Ronald Lundstrom Craig Tulig Kathleen Falls Joan Imrich Dana Torrey Marcy Engelstein Gary Breton Deepika Madan Raymond Nietupski Bruce Seitz Steven Connelly Steven McDougall Hershel Safer Rene Gibson Lynn Doucette-Stamm Karin Eiglmeier Staffan Bergh Stewart T. Cole Keith Robison
... [+28 authors] ...,
Laura Richterich
Jason Johnson
George M. Church
Jen-i Mao

First Published August 1, 1997

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Your search for returned 33 results

Understanding transcriptional regulation by integrative analysis of transcription factor binding data

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

Translating cancer ‘omics’ to improved outcomes

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

Efficient storage of high throughput DNA sequencing data using reference-based compression

High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells

The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance

An effective model for natural selection in promoters

A new strategy for genome assembly using short sequence reads and reduced representation libraries

The completion of the Mammalian Gene Collection (MGC)

The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

Enredo and Pecan: Genome-wide mammalian consistency-based multiple alignment with paralogs

Genome-wide nucleotide-level mammalian ancestor reconstruction

Confounding between recombination and selection, and the Ped/Pop method for detecting selection

An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)

Velvet: Algorithms for de novo short read assembly using de Bruijn graphs

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

The landscape of histone modifications across 1% of the human genome in five human cell lines

Identification of novel peptide hormones in the human proteome by hidden Markov model screening

Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags

The Ensembl Core Software Libraries

Sockeye: A 3D Environment for Comparative Genomics

GeneWise and Genomewise

An Overview of Ensembl

Comparison of Human Chromosome 21 Conserved Nongenic Sequences (CNGs) With the Mouse and Dog Genomes Shows That Their Selective Constraint Is Independent of Their Genic Environment

EnsMart: A Generic System for Fast and Flexible Access to Biological Data

cis-Regulatory Motifs Using Functional Networks" > Discovering Novel cis-Regulatory Motifs Using Functional Networks

The Bioperl Toolkit: Perl Modules for the Life Sciences

GeneWise in the Drosophila Annotation Experiment" > Using `GeneWise` in the Drosophila Annotation Experiment

Comparative Analysis of Noncoding Regions of 77 Orthologous Mouse and Human Gene Pairs

Mycobacterium leprae Genome" > Multiplex Sequencing of 1.5 Mb of the Mycobacterium leprae Genome

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Your search for returned 33 results