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Research

Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits

  • Kevin W. Currin
  • Hannah J. Perrin
  • Gautam K. Pandey
  • Abdalla A. Alkhawaja
  • Swarooparani Vadlamudi
  • Annie E. Musser Amy S. Etheridge K. Alaine Broadaway Jonathan D. Rosen Arushi Varshney Amarjit S. Chaudhry Paul J. Gallins Fred A. Wright Yi-hui Zhou Stephen C.J. Parker
  • ... [+10 authors] ...,
  • Laura M. Raffield
  • Erin G. Schuetz
  • Federico Innocenti
  • Karen L. Mohlke
  • First Published May 20, 2025
Research

Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits

  • Peter Orchard
  • Nandini Manickam
  • Christa Ventresca
  • Swarooparani Vadlamudi
  • Arushi Varshney
  • Vivek Rai Jeremy Kaplan Claudia Lalancette
  • ... [+3 authors] ...,
  • Karen L. Mohlke
  • Katherine Gallagher
  • Charles F. Burant
  • Stephen C.J. Parker
  • First Published November 23, 2021
Method

Accurate and comprehensive sequencing of personal genomes

  • Subramanian S. Ajay
  • Stephen C.J. Parker
  • Hatice Ozel Abaan
  • Karin V. Fuentes Fajardo
  • Elliott H. Margulies
  • First Published July 19, 2011
Letter

Complex selection on 5′ splice sites in intron-rich organisms

  • Manuel Irimia
  • Scott William Roy
  • Daniel E. Neafsey
  • Josep F. Abril
  • Jordi Garcia-Fernandez
  • Eugene V. Koonin
  • First Published September 10, 2009
LETTER

Evolution of protein domain promiscuity in eukaryotes

  • Malay Kumar Basu
  • Liran Carmel
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published January 29, 2008
Methods

Detection of DNA structural motifs in functional genomic elements

  • Jason A. Greenbaum
  • Stephen C.J. Parker
  • Thomas D. Tullius
  • First Published June 13, 2007
LETTER

Three distinct modes of intron dynamics in the evolution of eukaryotes

  • Liran Carmel
  • Yuri I. Wolf
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published May 10, 2007
LETTER

Evolutionarily conserved genes preferentially accumulate introns

  • Liran Carmel
  • Igor B. Rogozin
  • Yuri I. Wolf
  • Eugene V. Koonin
  • First Published May 10, 2007
LETTER

Origins and impact of constraints in evolution of gene families

  • Boris E. Shakhnovich
  • Eugene V. Koonin
  • First Published October 19, 2006
LETTER

Coelomata and Not Ecdysozoa: Evidence From Genome-Wide Phylogenetic Analysis

  • Yuri I. Wolf
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published January 5, 2004
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