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A deconvolution framework that uses single-cell sequencing plus a small benchmark data set for accurate analysis of cell type ratios in complex tissue samples

  • Shuai Guo
  • Xiaoqian Liu
  • Xuesen Cheng
  • Yujie Jiang
  • Shuangxi Ji
  • Qingnan Liang Andrew Koval Yumei Li Leah A. Owen Ivana K. Kim Ana Aparicio Sanghoon Lee Anil K. Sood Scott Kopetz John Paul Shen
  • ... [+10 authors] ...,
  • John N. Weinstein
  • Margaret M. DeAngelis
  • Rui Chen
  • Wenyi Wang
  • First Published November 25, 2024

Accelerated somatic mutation calling for whole-genome and whole-exome sequencing data from heterogenous tumor samples

  • Shuangxi Ji
  • Tong Zhu
  • Ankit Sethia
  • Wenyi Wang
  • First Published April 8, 2024

Complex selection on 5′ splice sites in intron-rich organisms

  • Manuel Irimia
  • Scott William Roy
  • Daniel E. Neafsey
  • Josep F. Abril
  • Jordi Garcia-Fernandez
  • Eugene V. Koonin
  • First Published September 10, 2009

Evolution of protein domain promiscuity in eukaryotes

  • Malay Kumar Basu
  • Liran Carmel
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published January 29, 2008

Three distinct modes of intron dynamics in the evolution of eukaryotes

  • Liran Carmel
  • Yuri I. Wolf
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published May 10, 2007

Evolutionarily conserved genes preferentially accumulate introns

  • Liran Carmel
  • Igor B. Rogozin
  • Yuri I. Wolf
  • Eugene V. Koonin
  • First Published May 10, 2007

Origins and impact of constraints in evolution of gene families

  • Boris E. Shakhnovich
  • Eugene V. Koonin
  • First Published October 19, 2006

Coelomata and Not Ecdysozoa: Evidence From Genome-Wide Phylogenetic Analysis

  • Yuri I. Wolf
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published January 5, 2004

Gene Loss, Protein Sequence Divergence, Gene Dispensability, Expression Level, and Interactivity Are Correlated in Eukaryotic Evolution

  • Dmitri M. Krylov
  • Yuri I. Wolf
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published October 2, 2003

The Role of Lineage-Specific Gene Family Expansion in the Evolution of Eukaryotes

  • Olivier Lespinet
  • Yuri I. Wolf
  • Eugene V. Koonin
  • L. Aravind
  • First Published July 1, 2002
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