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Analysis of a cell-free DNA–based cancer screening cohort links fragmentomic profiles, nuclease levels, and plasma DNA concentrations

  • Yasine Malki
  • Guannan Kang
  • W.K. Jacky Lam
  • Qing Zhou
  • Suk Hang Cheng
  • Peter P.H. Cheung Jinyue Bai Ming Lok Chan Chui Ting Lee Wenlei Peng Yiqiong Zhang Wanxia Gai Winsome W.S. Wong Mary-Jane L. Ma Wenshuo Li Xinzhou Xu Zhuoran Gao Irene O.L. Tse Huimin Shang
  • ... [+14 authors] ...,
  • L.Y. Lois Choy
  • Peiyong Jiang
  • K.C. Allen Chan
  • Y.M. Dennis Lo
  • First Published November 27, 2024

Complex selection on 5′ splice sites in intron-rich organisms

  • Manuel Irimia
  • Scott William Roy
  • Daniel E. Neafsey
  • Josep F. Abril
  • Jordi Garcia-Fernandez
  • Eugene V. Koonin
  • First Published September 10, 2009

Evolution of protein domain promiscuity in eukaryotes

  • Malay Kumar Basu
  • Liran Carmel
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published January 29, 2008

Three distinct modes of intron dynamics in the evolution of eukaryotes

  • Liran Carmel
  • Yuri I. Wolf
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published May 10, 2007

Evolutionarily conserved genes preferentially accumulate introns

  • Liran Carmel
  • Igor B. Rogozin
  • Yuri I. Wolf
  • Eugene V. Koonin
  • First Published May 10, 2007

Origins and impact of constraints in evolution of gene families

  • Boris E. Shakhnovich
  • Eugene V. Koonin
  • First Published October 19, 2006

Coelomata and Not Ecdysozoa: Evidence From Genome-Wide Phylogenetic Analysis

  • Yuri I. Wolf
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published January 5, 2004

Gene Loss, Protein Sequence Divergence, Gene Dispensability, Expression Level, and Interactivity Are Correlated in Eukaryotic Evolution

  • Dmitri M. Krylov
  • Yuri I. Wolf
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published October 2, 2003

The Role of Lineage-Specific Gene Family Expansion in the Evolution of Eukaryotes

  • Olivier Lespinet
  • Yuri I. Wolf
  • Eugene V. Koonin
  • L. Aravind
  • First Published July 1, 2002

Essential Genes Are More Evolutionarily Conserved Than Are Nonessential Genes in Bacteria

  • I. King Jordan
  • Igor B. Rogozin
  • Yuri I. Wolf
  • Eugene V. Koonin
  • First Published May 16, 2002
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