Method
High-throughput single-cell functional elucidation of neurodevelopmental disease–associated genes reveals convergent mechanisms altering neuronal differentiation
- First Published September 4, 2020
Research
Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders
- First Published April 27, 2015
Letter
Complex selection on 5′ splice sites in intron-rich organisms
- First Published September 10, 2009
LETTER
Three distinct modes of intron dynamics in the evolution of eukaryotes
- First Published May 10, 2007
LETTER
Evolutionarily conserved genes preferentially accumulate introns
- First Published May 10, 2007
LETTER
Origins and impact of constraints in evolution of gene families
- First Published October 19, 2006
Methods
A systematic model to predict transcriptional regulatory mechanisms based on overrepresentation of transcription factor binding profiles
- First Published January 31, 2006
LETTER
Coelomata and Not Ecdysozoa: Evidence From Genome-Wide Phylogenetic Analysis
- First Published January 5, 2004
LETTER
Gene Loss, Protein Sequence Divergence, Gene Dispensability, Expression Level, and Interactivity Are Correlated in Eukaryotic Evolution
- First Published October 2, 2003