Search | Genome Research

In memoriam

Jim Watson (1928–2025): a genomics visionary

Aravinda Chakravarti
Evan E. Eichler
Anne C. Ferguson-Smith
Richard A. Gibbs
Eric D. Green
John R. Inglis
Kateryna D. Makova
Richard M. Myers
Hillary E. Sussman

First Published July 23, 2026

Resource

Drosophila and C. elegans transcription factors reveal tissue-specific regulatory relationships" > Binding profiles for 961 Drosophila and C. elegans transcription factors reveal tissue-specific regulatory relationships

Michelle Kudron
Louis Gevirtzman
Alec Victorsen
Bridget C. Lear
Jiahao Gao
Jinrui Xu Swapna Samanta Emily Frink Adri Tran-Pearson Chau Huynh Dionne Vafeados Ann Hammonds William Fisher Martha Wall Greg Wesseling Vanessa Hernandez Zhichun Lin Mary Kasparian Kevin White Ravi Allada Mark Gerstein
... [+16 authors] ...,
LaDeana Hillier
Susan E. Celniker
Valerie Reinke
Robert H. Waterston

First Published October 22, 2024

In memoriam

C. Thomas Caskey (1938–2022)

Richard A. Gibbs
Aravinda Chakravarti
Evan E. Eichler
Eric D. Green
Richard M. Myers
Anne C. Ferguson-Smith
Kateryna D. Makova
Hillary E. Sussman

First Published February 17, 2022

In memoriam

Deborah A. Nickerson (1954 –2021)

Aravinda Chakravarti
Evan E. Eichler
Richard A. Gibbs
Eric D. Green
Richard M. Myers
Hillary E. Sussman

First Published January 24, 2022

Resource

Caenorhabditis elegans nematodes" > Comprehensive characterization of tissue-specific chromatin accessibility in L2 Caenorhabditis elegans nematodes

Timothy J. Durham
Riza M. Daza
Louis Gevirtzman
Darren A. Cusanovich
Olubusayo Bolonduro
William Stafford Noble
Jay Shendure
Robert H. Waterston

First Published April 22, 2021

Resource

C. elegans embryonic transcriptome with tissue, time, and alternative splicing resolution" > The C. elegans embryonic transcriptome with tissue, time, and alternative splicing resolution

Adam D. Warner
Louis Gevirtzman
LaDeana W. Hillier
Brent Ewing
Robert H. Waterston

First Published May 23, 2019

In memoriam

John Sulston (1942–2018)

Robert H. Waterston

First Published June 1, 2018

Resource

C. elegans" > The time-resolved transcriptome of C. elegans

Max E. Boeck
Chau Huynh
Lou Gevirtzman
Owen A. Thompson
Guilin Wang
Dionna M. Kasper
Valerie Reinke
LaDeana W. Hillier
Robert H. Waterston

First Published August 16, 2016

Resource

Caenorhabditis elegans" > The million mutation project: A new approach to genetics in Caenorhabditis elegans

Owen Thompson
Mark Edgley
Pnina Strasbourger
Stephane Flibotte
Brent Ewing
Ryan Adair Vinci Au Iasha Chaudhry Lisa Fernando Harald Hutter Armelle Kieffer Joanne Lau Norris Lee Angela Miller Greta Raymant Bin Shen Jay Shendure Jon Taylor
... [+13 authors] ...,
Emily H. Turner
LaDeana W. Hillier
Donald G. Moerman
Robert H. Waterston

First Published June 25, 2013

Research

C. elegans embryo" > Multidimensional regulation of gene expression in the C. elegans embryo

John Isaac Murray
Thomas J. Boyle
Elicia Preston
Dionne Vafeados
Barbara Mericle
Peter Weisdepp
... [+1 authors] ...,
Zhongying Zhao
Zhirong Bao
Max Boeck
Robert H. Waterston

First Published April 16, 2012

Research

XIST locus" > Comparative analysis of the primate X-inactivation center region and reconstruction of the ancestral primate XIST locus

Julie E. Horvath
Christina B. Sheedy
Stephanie L. Merrett
Abdoulaye Banire Diallo
David L. Swofford
NISC Comparative Sequencing Program
Eric D. Green
Huntington F. Willard

First Published April 25, 2011

Research

C. elegans trans-splicing" > A global analysis of C. elegans trans-splicing

Mary Ann Allen
LaDeana W. Hillier
Robert H. Waterston
Thomas Blumenthal

First Published December 22, 2010

Research

C. elegans" > Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans

Wei Niu
Zhi John Lu
Mei Zhong
Mihail Sarov
John I. Murray
Cathleen M. Brdlik Judith Janette Chao Chen Pedro Alves Elicia Preston Cindie Slightham Lixia Jiang Anthony A. Hyman Stuart K. Kim
... [+9 authors] ...,
Robert H. Waterston
Mark Gerstein
Michael Snyder
Valerie Reinke

First Published December 22, 2010

Method

C. elegans by integrating conservation, secondary structure, and high-throughput sequencing and array data" > Prediction and characterization of noncoding RNAs in C. elegans by integrating conservation, secondary structure, and high-throughput sequencing and array data

Zhi John Lu
Kevin Y. Yip
Guilin Wang
Chong Shou
LaDeana W. Hillier
Ekta Khurana Ashish Agarwal Raymond Auerbach Joel Rozowsky Chao Cheng Masaomi Kato David M. Miller Frank Slack
... [+8 authors] ...,
Michael Snyder
Robert H. Waterston
Valerie Reinke
Mark B. Gerstein

First Published December 22, 2010

Method

Systematic comparison of three genomic enrichment methods for massively parallel DNA sequencing

Jamie K. Teer
Lori L. Bonnycastle
Peter S. Chines
Nancy F. Hansen
Natsuyo Aoyama
Amy J. Swift Hatice Ozel Abaan Thomas J. Albert Elliott H. Margulies
... [+4 authors] ...,
Eric D. Green
Francis S. Collins
James C. Mullikin
Leslie G. Biesecker

First Published September 1, 2010

Resource

The completion of the Mammalian Gene Collection (MGC)

Gary Temple
Daniela S. Gerhard
Rebekah Rasooly
Elise A. Feingold
Peter J. Good
Cristen Robinson Allison Mandich Jeffrey G. Derge Jeanne Lewis Debonny Shoaf Francis S. Collins Wonhee Jang Lukas Wagner Carolyn M. Shenmen Leonie Misquitta Carl F. Schaefer Kenneth H. Buetow Tom I. Bonner Linda Yankie Ming Ward Lon Phan Alex Astashyn Garth Brown Catherine Farrell Jennifer Hart Melissa Landrum Bonnie L. Maidak Michael Murphy Terence Murphy Bhanu Rajput Lillian Riddick David Webb Janet Weber Wendy Wu Kim D. Pruitt Donna Maglott Adam Siepel Brona Brejova Mark Diekhans Rachel Harte Robert Baertsch Jim Kent David Haussler Michael Brent Laura Langton Charles L.G. Comstock Michael Stevens Chaochun Wei Marijke J. van Baren Kourosh Salehi-Ashtiani Ryan R. Murray Lila Ghamsari Elizabeth Mello Chenwei Lin Christa Pennacchio Kirsten Schreiber Nicole Shapiro Amber Marsh Elizabeth Pardes Troy Moore Anita Lebeau Mike Muratet Blake Simmons David Kloske Stephanie Sieja James Hudson Praveen Sethupathy Michael Brownstein Narayan Bhat Joseph Lazar Howard Jacob Chris E. Gruber Mark R. Smith John McPherson Angela M. Garcia Preethi H. Gunaratne Jiaqian Wu Donna Muzny Richard A. Gibbs Alice C. Young Gerard G. Bouffard Robert W. Blakesley Jim Mullikin Eric D. Green Mark C. Dickson Alex C. Rodriguez Jane Grimwood Jeremy Schmutz Richard M. Myers Martin Hirst Thomas Zeng Kane Tse Michelle Moksa Merinda Deng Kevin Ma Diana Mah Johnson Pang Greg Taylor Eric Chuah Athena Deng Keith Fichter Anne Go Stephanie Lee Jing Wang Malachi Griffith Ryan Morin Richard A. Moore Michael Mayo Sarah Munro Susan Wagner Steven J.M. Jones Robert A. Holt Marco A. Marra Sun Lu Shuwei Yang James Hartigan Marcus Graf Ralf Wagner Stanley Letovksy Jacqueline C. Pulido Keith Robison Dominic Esposito James Hartley
... [+118 authors] ...,
Vanessa E. Wall
Ralph F. Hopkins
Osamu Ohara
Stefan Wiemann

First Published September 18, 2009

Resource

The ClinSeq Project: Piloting large-scale genome sequencing for research in genomic medicine

Leslie G. Biesecker
James C. Mullikin
Flavia M. Facio
Clesson Turner
Praveen F. Cherukuri
Robert W. Blakesley Gerard G. Bouffard Peter S. Chines Pedro Cruz Nancy F. Hansen Jamie K. Teer Baishali Maskeri Alice C. Young Teri A. Manolio Alexander F. Wilson Toren Finkel Paul Hwang Andrew Arai Alan T. Remaley
... [+14 authors] ...,
Vandana Sachdev
Robert Shamburek
Richard O. Cannon
Eric D. Green

First Published July 14, 2009

LETTER

Comparative sequence analysis of primate subtelomeres originating from a chromosome fission event

M. Katharine Rudd
RaeLynn M. Endicott
Cynthia Friedman
Megan Walker
Janet M. Young
Kazutoyo Osoegawa
Pieter J. de Jong
Eric D. Green
Barbara J. Trask

First Published October 24, 2008

ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

Elliott H. Margulies
Gregory M. Cooper
George Asimenos
Daryl J. Thomas
Colin N. Dewey
Adam Siepel Ewan Birney Damian Keefe Ariel S. Schwartz Minmei Hou James Taylor Sergey Nikolaev Juan I. Montoya-Burgos Ari Löytynoja Simon Whelan Fabio Pardi Tim Massingham James B. Brown Peter Bickel Ian Holmes James C. Mullikin Abel Ureta-Vidal Benedict Paten Eric A. Stone Kate R. Rosenbloom W. James Kent Gerard G. Bouffard Xiaobin Guan Nancy F. Hansen Jacquelyn R. Idol Valerie V.B. Maduro Baishali Maskeri Jennifer C. McDowell Morgan Park Pamela J. Thomas Alice C. Young Robert W. Blakesley Donna M. Muzny Erica Sodergren David A. Wheeler Kim C. Worley Huaiyang Jiang George M. Weinstock Richard A. Gibbs Tina Graves Robert Fulton Elaine R. Mardis Richard K. Wilson Michele Clamp James Cuff Sante Gnerre David B. Jaffe Jean L. Chang Kerstin Lindblad-Toh Eric S. Lander Angie Hinrichs Heather Trumbower Hiram Clawson Ann Zweig Robert M. Kuhn Galt Barber Rachel Harte Donna Karolchik Matthew A. Field Richard A. Moore Carrie A. Matthewson Jacqueline E. Schein Marco A. Marra Stylianos E. Antonarakis Serafim Batzoglou Nick Goldman Ross Hardison David Haussler
... [+68 authors] ...,
Webb Miller
Lior Pachter
Eric D. Green
Arend Sidow

First Published June 13, 2007

LETTER

WFDC locus in the primate lineage" > Comparative sequence analyses reveal rapid and divergent evolutionary changes of the WFDC locus in the primate lineage

Belen Hurle
Willie Swanson
Eric D. Green

First Published January 31, 2007

RESOURCE

Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling" > Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling

Ryan D. Morin
Elbert Chang
Anca Petrescu
Nancy Liao
Malachi Griffith
Robert Kirkpatrick Yaron S. Butterfield Alice C. Young Jeffrey Stott Sarah Barber Ryan Babakaiff Mark C. Dickson Corey Matsuo David Wong George S. Yang Duane E. Smailus Keith D. Wetherby Peggy N. Kwong Jane Grimwood Charles P. Brinkley Mabel Brown-John Natalie D. Reddix-Dugue Michael Mayo Jeremy Schmutz Jaclyn Beland Morgan Park Susan Gibson Teika Olson Gerard G. Bouffard Miranda Tsai Ruth Featherstone Steve Chand Asim S. Siddiqui Wonhee Jang Ed Lee Steven L. Klein Robert W. Blakesley Barry R. Zeeberg Sudarshan Narasimhan John N. Weinstein Christa Prange Pennacchio Richard M. Myers Eric D. Green Lukas Wagner
... [+39 authors] ...,
Daniela S. Gerhard
Marco A. Marra
Steven J.M. Jones
Robert A. Holt

First Published May 3, 2006

LETTER

A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications

Xinwei She
Ge Liu
Mario Ventura
Shaying Zhao
Doriana Misceo
Roberta Roberto Maria Francesca Cardone
... [+2 authors] ...,
Mariano Rocchi
Eric D. Green
Nicoletta Archidiacano
Evan E. Eichler

First Published April 10, 2006

PERSPECTIVE

C. elegans: So many genes, such a little worm" > Genomics in C. elegans: So many genes, such a little worm

LaDeana W. Hillier
Alan Coulson
John I. Murray
Zhirong Bao
John E. Sulston
Robert H. Waterston

First Published December 8, 2005

ARTICLE

Distribution and intensity of constraint in mammalian genomic sequence

Gregory M. Cooper
Eric A. Stone
George Asimenos
Eric D. Green
Serafim Batzoglou
Arend Sidow

First Published June 17, 2005

ARTICLE

Interchromosomal segmental duplications of the pericentromeric region on the human Y chromosome

Stefan Kirsch
Birgit Weiß
Tracie L. Miner
Robert H. Waterston
Royden A. Clark
Evan E. Eichler
Claudia Münch
Werner Schempp
Gudrun Rappold

First Published January 14, 2005

LETTER

Caenorhabditis elegans muscle genes" > Novel transcription regulatory elements in Caenorhabditis elegans muscle genes

Debraj GuhaThakurta
Lawrence A. Schriefer
Robert H. Waterston
Gary D. Stormo

First Published December 1, 2004

LETTER

Reconstructing large regions of an ancestral mammalian genome in silico

Mathieu Blanchette
Eric D. Green
Webb Miller
David Haussler

First Published December 1, 2004

LETTER

An intermediate grade of finished genomic sequence suitable for comparative analyses

Robert W. Blakesley
Nancy F. Hansen
James C. Mullikin
Pamela J. Thomas
Jennifer C. McDowell
Baishali Maskeri Alice C. Young Beatrice Benjamin Shelise Y. Brooks Bradley I. Coleman Jyoti Gupta Shi-Ling Ho Eric M. Karlins Quino L. Maduro Sirintorn Stantripop Cyrus Tsurgeon Jennifer L. Vogt Michelle A. Walker
... [+13 authors] ...,
Catherine A. Masiello
Xiaobin Guan
Gerard G. Bouffard
Eric D. Green

First Published October 12, 2004

RESOURCE

Aligning Multiple Genomic Sequences With the Threaded Blockset Aligner

Mathieu Blanchette
W. James Kent
Cathy Riemer
Laura Elnitski
Arian F.A. Smit
Krishna M. Roskin Robert Baertsch Kate Rosenbloom
... [+3 authors] ...,
Hiram Clawson
Eric D. Green
David Haussler
Webb Miller

First Published April 1, 2004

ARTICLE

Strongyloides stercoralis and Caenorhabditis elegans" > Comparative Genomics of Gene Expression in the Parasitic and Free-Living Nematodes Strongyloides stercoralis and Caenorhabditis elegans

Makedonka Mitreva
James P. McCarter
John Martin
Mike Dante
Todd Wylie
Brandi Chiapelli
... [+1 authors] ...,
Deana Pape
Sandra W. Clifton
Thomas B. Nutman
Robert H. Waterston

First Published February 2, 2004

ARTICLE

Identification and Characterization of Multi-Species Conserved Sequences

Elliott H. Margulies
Mathieu Blanchette
David Haussler
Eric D. Green

First Published December 1, 2003

LETTER

Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes

Gregory M. Cooper
Michael Brudno
NISC Comparative Sequencing Program
Eric D. Green
Serafim Batzoglou
Arend Sidow

First Published May 1, 2003

METHODS

Software for Automated Analysis of DNA Fingerprinting Gels

Daniel R. Fuhrmann
Martin I. Krzywinski
Readman Chiu
Parvaneh Saeedi
Jacqueline E. Schein
Ian E. Bosdet Asif Chinwalla LaDeana W. Hillier
... [+3 authors] ...,
Robert H. Waterston
John D. McPherson
Steven J.M. Jones
Marco A. Marra

First Published May 1, 2003

METHODS

LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA

Michael Brudno
Chuong B. Do
Gregory M. Cooper
Michael F. Kim
Eugene Davydov
NISC Comparative Sequencing Program
Eric D. Green
Arend Sidow
Serafim Batzoglou

First Published March 12, 2003

LETTER

Analysis of Primate Genomic Variation Reveals a Repeat-Driven Expansion of the Human Genome

Ge Liu
NISC Comparative Sequencing Program
Shaying Zhao
Jeffrey A. Bailey
S. Cenk Sahinalp
Can Alkan
Eray Tuzun
Eric D. Green
Evan E. Eichler

First Published March 1, 2003

LETTER

Gene Discovery in the Apicomplexa as Revealed by EST Sequencing and Assembly of a Comparative Gene Database

Li Li
Brian P. Brunk
Jessica C. Kissinger
Deana Pape
Keliang Tang
Robert H. Cole John Martin Todd Wylie Mike Dante Steven J. Fogarty Daniel K. Howe Paul Liberator Carmen Diaz Jennifer Anderson Michael White Maria E. Jerome Emily A. Johnson Jay A. Radke Christian J. Stoeckert
... [+14 authors] ...,
Robert H. Waterston
Sandra W. Clifton
David S. Roos
L. David Sibley

First Published March 1, 2003

LETTER

Pericentromeric Duplications in the Laboratory Mouse

James W. Thomas
Mary G. Schueler
Tyrone J. Summers
Robert W. Blakesley
Jennifer C. McDowell
Pamela J. Thomas Jacquelyn R. Idol Valerie V.B. Maduro Shih-Queen Lee-Lin Jeffrey W. Touchman
... [+5 authors] ...,
Gerard G. Bouffard
Stephen M. Beckstrom-Sternberg
NISC Comparative Sequencing Program
Eric D. Green

First Published December 30, 2002

METHODS

Generalized Gap Model for Bacterial Artificial Chromosome Clone Fingerprint Mapping and Shotgun Sequencing

Michael C. Wendl
Robert H. Waterston

First Published December 1, 2002

METHODS

Parallel Construction of Orthologous Sequence-Ready Clone Contig Maps in Multiple Species

James W. Thomas
Arjun B. Prasad
Tyrone J. Summers
Shih-Queen Lee-Lin
Valerie V.B. Maduro
Jacquelyn R. Idol
... [+1 authors] ...,
Joseph F. Ryan
Pamela J. Thomas
Jennifer C. McDowell
Eric D. Green

First Published August 1, 2002

REPORT

3.3 Mb of Mouse Genomic Sequence Orthologous to the Region of Human Chromosome 7q11.23 Implicated in Williams Syndrome " > Generation and Comparative Analysis of ∼3.3 Mb of Mouse Genomic Sequence Orthologous to the Region of Human Chromosome 7q11.23 Implicated in Williams Syndrome

Udaya DeSilva
Laura Elnitski
Jacquelyn R. Idol
Johannah L. Doyle
Weiniu Gan
James W. Thomas Scott Schwartz Nicole L. Dietrich Stephen M. Beckstrom-Sternberg Jennifer C. McDowell Robert W. Blakesley Gerard G. Bouffard
... [+7 authors] ...,
Pamela J. Thomas
Jeffrey W. Touchman
Webb Miller
Eric D. Green

First Published January 1, 2002

ARTICLE

Saccharomyces Genomes to Identify Functional Elements by Comparative DNA Sequence Analysis" > Surveying Saccharomyces Genomes to Identify Functional Elements by Comparative DNA Sequence Analysis

Paul F. Cliften
LaDeana W. Hillier
Lucinda Fulton
Tina Graves
Tracie Miner
Warren R. Gish
Robert H. Waterston
Mark Johnston

First Published July 1, 2001

COMMENTARY

The Human Genome Sequence Expedition: Views from the “Base Camp”

Eric D. Green
Aravinda Chakravarti

First Published May 1, 2001

METHODS

Theories and Applications for Sequencing Randomly Selected Clones

Michael C. Wendl
Marco A. Marra
LaDeana W. Hillier
Asif T. Chinwalla
Richard K. Wilson
Robert H. Waterston

First Published January 18, 2001

REPORT

Comparative Genome Mapping in the Sequence-based Era: Early Experience with Human Chromosome 7

James W. Thomas
Tyrone J. Summers
Shih-Queen Lee-Lin
Valerie V. Braden Maduro
Jacquelyn R. Idol
Stephen D. Mastrian
Joseph F. Ryan
D. Curtis Jamison
Eric D. Green

First Published May 1, 2000

REPORT

CTNS): Complete Sequencing of a 200-kb Segment and Discovery of a Novel Gene within the Common Cystinosis-Causing Deletion" > The Genomic Region Encompassing the Nephropathic Cystinosis Gene (CTNS): Complete Sequencing of a 200-kb Segment and Discovery of a Novel Gene within the Common Cystinosis-Causing Deletion

Jeffrey W. Touchman
Yair Anikster
Nicole L. Dietrich
Valerie V. Braden Maduro
Geraldine McDowell
Vorasuk Shotelersuk
... [+1 authors] ...,
Gerard G. Bouffard
Stephen M. Beckstrom-Sternberg
William A. Gahl
Eric D. Green

First Published February 1, 2000

LETTER

CMT2D Locus: Refined Genetic Position and Construction of a Bacterial Clone-Based Physical Map" > The CMT2D Locus: Refined Genetic Position and Construction of a Bacterial Clone-Based Physical Map

Rachel E. Ellsworth
Victor Ionasescu
Charles Searby
Val C. Sheffield
Valerie V. Braden
Tamara A. Kucaba
John D. McPherson
Marco A. Marra
Eric D. Green

First Published June 1, 1999

LETTER

Comparative Mapping of the Region of Human Chromosome 7 Deleted in Williams Syndrome

Udaya DeSilva
Hillary Massa
Barbara J. Trask
Eric D. Green

First Published May 1, 1999

LETTER

High Throughput Fingerprint Analysis of Large-Insert Clones

Marco A. Marra
Tamara A. Kucaba
Nicole L. Dietrich
Eric D. Green
Buddy Brownstein
Richard K. Wilson
... [+1 authors] ...,
Ken M. McDonald
LaDeana W. Hillier
John D. McPherson
Robert H. Waterston

First Published November 1, 1997

RESEARCH

A Physical Map of Human Chromosome 7: An Integrated YAC Contig Map with Average STS Spacing of 79 kb

Gerard G. Bouffard
Jacquelyn R. Idol
Valerie V. Braden
Leslie M. Iyer
Aimee F. Cunningham
Lauren A. Weintraub Jeffrey W. Touchman Rose M. Mohr-Tidwell Dale C. Peluso Robert S. Fulton
... [+5 authors] ...,
Melinda S. Ueltzen
Jean Weissenbach
Charles L. Magness
Eric D. Green

First Published July 1, 1997

Filter results by:

Filter by Author

Filter by Article type

Your search for returned 49 results

In memoriam

Resource

In memoriam

In memoriam

Resource

Resource

In memoriam

Resource

Resource

Research

Research

Research

Research

Method

Method

Resource

Resource

LETTER

ARTICLE

LETTER

RESOURCE

LETTER

PERSPECTIVE

ARTICLE

ARTICLE

LETTER

LETTER

LETTER

RESOURCE

ARTICLE

ARTICLE

LETTER

METHODS

METHODS

LETTER

LETTER

LETTER

METHODS

METHODS

REPORT

ARTICLE

COMMENTARY

METHODS

REPORT

REPORT

LETTER

LETTER

LETTER

RESEARCH