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Method

MAPLE enables ultrasensitive detection of low-frequency cfDNA methylation haplotypes using short capture probes with cost-efficient performance

  • First Published June 16, 2026
Method

scSHEFT enables multiomics label transfer from scRNA-seq to scATAC-seq through dual alignment

  • First Published January 20, 2026
Method

Accurate estimation of intraspecific microbial gene content variation in metagenomic data with MIDAS v3 and StrainPGC

  • First Published April 10, 2025
Method

Targeted, programmable, and precise tandem duplication in the mammalian genome

  • First Published June 9, 2023
Research

Long-read sequencing of 111 rice genomes reveals significantly larger pan-genomes

  • First Published April 8, 2022
Method

Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA

  • First Published June 17, 2021
Method

Predicting unrecognized enhancer-mediated genome topology by an ensemble machine learning model

  • First Published November 12, 2020
Research

Sequence determinants of polyadenylation-mediated regulation

  • First Published September 17, 2019
Research

Systematic interrogation of human promoters

  • First Published January 8, 2019
Corrigendum

Corrigendum: Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators

  • First Published March 1, 2017
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