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Method

Accurate estimation of intraspecific microbial gene content variation in metagenomic data with MIDAS v3 and StrainPGC

  • First Published April 10, 2025
Method

Accurate sequencing of DNA motifs able to form alternative (non-B) structures

  • First Published July 11, 2023
Research

Selection and thermostability suggest G-quadruplexes are novel functional elements of the human genome

  • First Published June 29, 2021
Research

Sequence determinants of polyadenylation-mediated regulation

  • First Published September 17, 2019
Research

Systematic interrogation of human promoters

  • First Published January 8, 2019
Research

Long-read sequencing technology indicates genome-wide effects of non-B DNA on polymerization speed and error rate

  • First Published November 6, 2018
Corrigendum

Corrigendum: Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators

  • First Published March 1, 2017
Research

Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators

  • First Published December 13, 2016
Corrigendum

Corrigendum: A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome?

  • First Published October 3, 2016
Research

Noise in gene expression is coupled to growth rate

  • First Published September 9, 2015
Corrigendum

Corrigendum: Unraveling determinants of transcription factor binding outside the core binding site

  • First Published September 1, 2015
Research

Core promoter sequence in yeast is a major determinant of expression level

  • First Published May 12, 2015
Method

Unraveling determinants of transcription factor binding outside the core binding site

  • First Published March 11, 2015
Research

Molecular dissection of the genetic mechanisms that underlie expression conservation in orthologous yeast ribosomal promoters

  • First Published October 7, 2014
Method

Probing the effect of promoters on noise in gene expression using thousands of designed sequences

  • First Published July 16, 2014
Resource

Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach

  • First Published August 15, 2013
Research

Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise

  • First Published February 12, 2013
Research

A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome?

  • First Published March 28, 2012
Research

Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters

  • First Published October 18, 2011
Research

A matter of life or death: How microsatellites emerge in and vanish from the human genome

  • First Published October 12, 2011
Research

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

  • First Published July 27, 2011
Research

C. elegans" > High nucleosome occupancy is encoded at X-linked gene promoters in C. elegans

  • First Published December 22, 2010
Research

Overlapping codes within protein-coding sequences

  • First Published September 14, 2010
Research

p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy

  • First Published August 17, 2010
Article

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

  • First Published November 3, 2009
Resource

Windshield splatter analysis with the Galaxy metagenomic pipeline

  • First Published October 9, 2009
Letter

Ride the wavelet: A multiscale analysis of genomic contexts flanking small insertions and deletions

  • First Published June 5, 2009
Methods

Incorporating nucleosomes into thermodynamic models of transcription regulation

  • First Published May 18, 2009
LETTER

Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif

  • First Published September 25, 2008
Methods

cis-regulatory motifs in human core promoters" > Systematic functional characterization of cis-regulatory motifs in human core promoters

  • First Published February 6, 2008
LETTER

The genome-wide determinants of human and chimpanzee microsatellite evolution

  • First Published November 21, 2007
LETTER

cis-regulatory elements using comparative genomics: Some lessons from ENCODE data" > Finding cis-regulatory elements using comparative genomics: Some lessons from ENCODE data

  • First Published June 13, 2007
Methods

ESPERR: Learning strong and weak signals in genomic sequence alignments to identify functional elements

  • First Published October 19, 2006
LETTER

cis-regulatory modules" > Experimental validation of predicted mammalian erythroid cis-regulatory modules

  • First Published October 12, 2006
Methods

Regulatory Potential Scores From Genome-Wide Three-Way Alignments of Human, Mouse, and Rat

  • First Published April 1, 2004
LETTER

Insertions and Deletions Are Male Biased Too: A Whole-Genome Analysis in Rodents

  • First Published April 1, 2004
ARTICLE

Patterns of Insertions and Their Covariation With Substitutions in the Rat, Mouse, and Human Genomes

  • First Published April 1, 2004
LETTER

Distinguishing Regulatory DNA From Neutral Sites

  • First Published January 1, 2003
LETTER

Gene Length and Proximity to Neighbors Affect Genome-Wide Expression Levels

  • First Published January 1, 2003
ARTICLE

Covariation in Frequencies of Substitution, Deletion, Transposition, and Recombination During Eutherian Evolution

  • First Published January 1, 2003
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