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Research

Analysis of canine gene constraint identifies new variants for orofacial clefts and stature

Reuben M. Buckley
Nüket Bilgen
Alexander C. Harris
Peter Savolainen
Cafer Tepeli
Metin Erdoğan Aitor Serres Armero Dayna L. Dreger Frank G. van Steenbeek Marjo K. Hytönen Heidi G. Parker Jessica Hale
... [+7 authors] ...,
Hannes Lohi
Bengi Çınar Kul
Adam R. Boyko
Elaine A. Ostrander

First Published March 24, 2025

Research

Copy number variation underlies complex phenotypes in domestic dog breeds and other canids

Aitor Serres-Armero
Brian W. Davis
Inna S. Povolotskaya
Carlos Morcillo-Suarez
Jocelyn Plassais
David Juan
Elaine A. Ostrander
Tomas Marques-Bonet

First Published April 16, 2021

Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

Myungjin Jo
Ah Young Chung
Nozomu Yachie
Minchul Seo
Hyejin Jeon
Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
... [+4 authors] ...,
Marc Vidal
Hae Chul Park
Frederick P. Roth
Kyoungho Suk

First Published June 8, 2017

Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

Song Sun
Fan Yang
Guihong Tan
Michael Costanzo
Rose Oughtred
Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
... [+10 authors] ...,
Brenda J. Andrews
Charles Boone
Kara Dolinski
Frederick P. Roth

First Published March 14, 2016

Research

Comparison against 186 canid whole-genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor

Brennan Decker
Brian W. Davis
Maud Rimbault
Adrienne H. Long
Eric Karlins
Vidhya Jagannathan Rebecca Reiman Heidi G. Parker Cord Drögemüller Jason J. Corneveaux Erica S. Chapman Jeffery M. Trent Tosso Leeb
... [+8 authors] ...,
Matthew J. Huentelman
Robert K. Wayne
Danielle M. Karyadi
Elaine A. Ostrander

First Published July 31, 2015

Research

Derived variants at six genes explain nearly half of size reduction in dog breeds

Maud Rimbault
Holly C. Beale
Jeffrey J. Schoenebeck
Barbara C. Hoopes
Jeremy J. Allen
Paul Kilroy-Glynn
Robert K. Wayne
Nathan B. Sutter
Elaine A. Ostrander

First Published September 11, 2013

Research

A genome-wide perspective on the evolutionary history of enigmatic wolf-like canids

Bridgett M. vonHoldt
John P. Pollinger
Dent A. Earl
James C. Knowles
Adam R. Boyko
Heidi Parker Eli Geffen Malgorzata Pilot Wlodzimierz Jedrzejewski Bogumila Jedrzejewska Vadim Sidorovich Claudia Greco Ettore Randi Marco Musiani Roland Kays
... [+10 authors] ...,
Carlos D. Bustamante
Elaine A. Ostrander
John Novembre
Robert K. Wayne

First Published May 12, 2011

Resource

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

Kourosh Salehi-Ashtiani
Chenwei Lin
Tong Hao
Yun Shen
David Szeto
Xinping Yang Lila Ghamsari HanJoo Lee Changyu Fan Ryan R. Murray Stuart Milstein Nenad Svrzikapa
... [+7 authors] ...,
Michael E. Cusick
Frederick P. Roth
David E. Hill
Marc Vidal

First Published October 2, 2009

Methods

Quantitative phenotyping via deep barcode sequencing

Andrew M. Smith
Lawrence E. Heisler
Joseph Mellor
Fiona Kaper
Michael J. Thompson
Mark Chee
Frederick P. Roth
Guri Giaever
Corey Nislow

First Published July 21, 2009

ARTICLE

Breed relationships facilitate fine-mapping studies: A 7.8-kb deletion cosegregates with Collie eye anomaly across multiple dog breeds

Heidi G. Parker
Anna V. Kukekova
Dayna T. Akey
Orly Goldstein
Ewen F. Kirkness
Kathleen C. Baysac
... [+1 authors] ...,
Dana S. Mosher
Gustavo D. Aguirre
Gregory M. Acland
Elaine A. Ostrander

First Published October 4, 2007

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