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Method

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

  • Jonathan S. Brammeld
  • Mia Petljak
  • Inigo Martincorena
  • Steven P. Williams
  • Luz Garcia Alonso
  • Alba Dalmases Beatriz Bellosillo Carla Daniela Robles-Espinoza Stacey Price Syd Barthorpe Patrick Tarpey Constantine Alifrangis Graham Bignell Joana Vidal Jamie Young Lucy Stebbings Kathryn Beal Michael R. Stratton Julio Saez-Rodriguez
  • ... [+14 authors] ...,
  • Mathew Garnett
  • Clara Montagut
  • Francesco Iorio
  • Ultan McDermott
  • First Published February 8, 2017
Corrigendum

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

  • Young Seok Ju
  • Jose M.C. Tubio
  • William Mifsud
  • Beiyuan Fu
  • Helen R. Davies
  • Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
  • ... [+39 authors] ...,
  • Fengtang Yang
  • Serena Nik-Zainal
  • Peter J. Campbell
  • Michael R. Stratton
  • First Published May 2, 2016
Research

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

  • Young Seok Ju
  • Jose M.C. Tubio
  • William Mifsud
  • Beiyuan Fu
  • Helen R. Davies
  • Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
  • ... [+39 authors] ...,
  • Fengtang Yang
  • Serena Nik-Zainal
  • Peter J. Campbell
  • Michael R. Stratton
  • First Published May 11, 2015
Research

C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency" > C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

  • Bettina Meier
  • Susanna L. Cooke
  • Joerg Weiss
  • Aymeric P. Bailly
  • Ludmil B. Alexandrov
  • John Marshall Keiran Raine Mark Maddison
  • ... [+3 authors] ...,
  • Elizabeth Anderson
  • Michael R. Stratton
  • Anton Gartner
  • Peter J. Campbell
  • First Published July 16, 2014
Method

Estimation of rearrangement phylogeny for cancer genomes

  • Chris D. Greenman
  • Erin D. Pleasance
  • Scott Newman
  • Fengtang Yang
  • Beiyuan Fu
  • Serena Nik-Zainal David Jones King Wai Lau Nigel Carter
  • ... [+4 authors] ...,
  • Paul A.W. Edwards
  • P. Andrew Futreal
  • Michael R. Stratton
  • Peter J. Campbell
  • First Published October 12, 2011
Letter

Population genomics in a disease targeted primary cell model

  • Elin Grundberg
  • Tony Kwan
  • Bing Ge
  • Kevin C.L. Lam
  • Vonda Koka
  • Andreas Kindmark Hans Mallmin Joana Dias Dominique J. Verlaan Manon Ouimet Daniel Sinnett Fernando Rivadeneira Karol Estrada Albert Hofman Joyce M. van Meurs André Uitterlinden Patrick Beaulieu Alexandru Graziani Eef Harmsen Östen Ljunggren Claes Ohlsson
  • ... [+16 authors] ...,
  • Dan Mellström
  • Magnus K. Karlsson
  • Olle Nilsson
  • Tomi Pastinen
  • First Published August 4, 2009
Methods

A probabilistic approach for SNP discovery in high-throughput human resequencing data

  • Rose Hoberman
  • Joana Dias
  • Bing Ge
  • Eef Harmsen
  • Michael Mayhew
  • Dominique J. Verlaan
  • ... [+1 authors] ...,
  • Tony Kwan
  • Ken Dewar
  • Mathieu Blanchette
  • Tomi Pastinen
  • First Published July 15, 2009
Methods

cis-regulatory variation in human haplotypes" > Targeted screening of cis-regulatory variation in human haplotypes

  • Dominique J. Verlaan
  • Bing Ge
  • Elin Grundberg
  • Rose Hoberman
  • Kevin C.L. Lam
  • Vonda Koka Joana Dias Scott Gurd Nicolas W. Martin Hans Mallmin Olof Nilsson
  • ... [+6 authors] ...,
  • Eef Harmsen
  • Ken Dewar
  • Tony Kwan
  • Tomi Pastinen
  • First Published October 29, 2008
LETTER

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

  • Graham R. Bignell
  • Thomas Santarius
  • Jessica C.M. Pole
  • Adam P. Butler
  • Janet Perry
  • Erin Pleasance Chris Greenman Andrew Menzies Sheila Taylor Sarah Edkins Peter Campbell Michael Quail Bob Plumb Lucy Matthews Kirsten McLay Paul A.W. Edwards
  • ... [+11 authors] ...,
  • Jane Rogers
  • Richard Wooster
  • P. Andrew Futreal
  • Michael R. Stratton
  • First Published August 3, 2007
Methods

Decoding the fine-scale structure of a breast cancer genome and transcriptome

  • Stanislav Volik
  • Benjamin J. Raphael
  • Guiqing Huang
  • Michael R. Stratton
  • Graham Bignel
  • John Murnane John H. Brebner Krystyna Bajsarowicz Pamela L. Paris Quanzhou Tao David Kowbel Anna Lapuk Dmitri A. Shagin Irina A. Shagina Joe W. Gray
  • ... [+10 authors] ...,
  • Jan-Fang Cheng
  • Pieter J. de Jong
  • Pavel Pevzner
  • Colin Collins
  • First Published February 3, 2006
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