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Method

3′-end ligation sequencing is a sensitive method to detect DNA nicks at potential sites of off-target activity induced by prime editors

  • Jacob Stewart-Ornstein
  • Matthew J. Irby
  • Marina K. Lilieholm
  • Dylan Laprise
  • Maria D. Collier
  • Thomas Aunins
  • ... [+1 authors] ...,
  • Dewi Harjanto
  • Aaron N. Chang
  • Deepak Reyon
  • Jeremy S. Duffield
  • First Published August 5, 2025
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