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Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia

  • Lili Wang
  • Jean Fan
  • Joshua M. Francis
  • George Georghiou
  • Sarah Hergert
  • Shuqiang Li Rutendo Gambe Chensheng W. Zhou Chunxiao Yang Sheng Xiao Paola Dal Cin Michaela Bowden Dylan Kotliar Sachet A. Shukla Jennifer R. Brown Donna Neuberg Dario R. Alessi
  • ... [+12 authors] ...,
  • Cheng-Zhong Zhang
  • Peter V. Kharchenko
  • Kenneth J. Livak
  • Catherine J. Wu
  • First Published July 5, 2017

Complex selection on 5′ splice sites in intron-rich organisms

  • Manuel Irimia
  • Scott William Roy
  • Daniel E. Neafsey
  • Josep F. Abril
  • Jordi Garcia-Fernandez
  • Eugene V. Koonin
  • First Published September 10, 2009

Evolution of protein domain promiscuity in eukaryotes

  • Malay Kumar Basu
  • Liran Carmel
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published January 29, 2008

Three distinct modes of intron dynamics in the evolution of eukaryotes

  • Liran Carmel
  • Yuri I. Wolf
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published May 10, 2007

Evolutionarily conserved genes preferentially accumulate introns

  • Liran Carmel
  • Igor B. Rogozin
  • Yuri I. Wolf
  • Eugene V. Koonin
  • First Published May 10, 2007

Origins and impact of constraints in evolution of gene families

  • Boris E. Shakhnovich
  • Eugene V. Koonin
  • First Published October 19, 2006

Coelomata and Not Ecdysozoa: Evidence From Genome-Wide Phylogenetic Analysis

  • Yuri I. Wolf
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published January 5, 2004

Gene Loss, Protein Sequence Divergence, Gene Dispensability, Expression Level, and Interactivity Are Correlated in Eukaryotic Evolution

  • Dmitri M. Krylov
  • Yuri I. Wolf
  • Igor B. Rogozin
  • Eugene V. Koonin
  • First Published October 2, 2003

The Role of Lineage-Specific Gene Family Expansion in the Evolution of Eukaryotes

  • Olivier Lespinet
  • Yuri I. Wolf
  • Eugene V. Koonin
  • L. Aravind
  • First Published July 1, 2002

Essential Genes Are More Evolutionarily Conserved Than Are Nonessential Genes in Bacteria

  • I. King Jordan
  • Igor B. Rogozin
  • Yuri I. Wolf
  • Eugene V. Koonin
  • First Published May 16, 2002
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