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Resource

Precision environmental health monitoring by longitudinal exposome and multi-omics profiling

  • First Published June 6, 2022
Method

Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome

  • First Published December 1, 2017
Corrigendum

Corrigendum: Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells

  • First Published September 1, 2015
Research

Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells

  • First Published March 19, 2015
Research

RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts

  • First Published December 18, 2014
Research

Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes

  • First Published November 3, 2014
Research

Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia" > Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia

  • First Published September 15, 2014
Resource

Annotation of functional variation in personal genomes using RegulomeDB

  • First Published September 5, 2012
Resource

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

  • First Published September 5, 2012
Method

Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements

  • First Published September 5, 2012
Research

A highly integrated and complex PPARGC1A transcription factor binding network in HepG2 cells

  • First Published September 5, 2012
Research

Understanding transcriptional regulation by integrative analysis of transcription factor binding data

  • First Published September 5, 2012
Resource

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

  • First Published September 5, 2012
Method

Linking disease associations with regulatory information in the human genome

  • First Published September 5, 2012
Research

Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs

  • First Published September 5, 2012
Method

Preparation of high-quality next-generation sequencing libraries from picogram quantities of target DNA

  • First Published November 16, 2011
Research

PRDM9 coincides with stabilization of the recombination landscape in the dog genome" > Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome

  • First Published October 17, 2011
Review

What fraction of the human genome is functional?

  • First Published August 29, 2011
Research

Natural genetic variation caused by small insertions and deletions in the human genome

  • First Published April 1, 2011
Resource

CNVnator: An approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing

  • First Published February 7, 2011
Research

C. elegans" > Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans

  • First Published December 22, 2010
Method

C. elegans by integrating conservation, secondary structure, and high-throughput sequencing and array data" > Prediction and characterization of noncoding RNAs in C. elegans by integrating conservation, secondary structure, and high-throughput sequencing and array data

  • First Published December 22, 2010
Resource

Candida albicans using RNA-seq" > Comprehensive annotation of the transcriptome of the human fungal pathogen Candida albicans using RNA-seq

  • First Published September 1, 2010
Research

A ChIP-seq defined genome-wide map of vitamin D receptor binding: Associations with disease and evolution

  • First Published August 24, 2010
Research

Massive turnover of functional sequence in human and other mammalian genomes

  • First Published August 6, 2010
Method

Genome assembly quality: Assessment and improvement using the neutral indel model

  • First Published March 19, 2010
Methods

MSB: A mean-shift-based approach for the analysis of structural variation in the genome

  • First Published November 26, 2008
LETTER

Analysis of copy number variants and segmental duplications in the human genome: Evidence for a change in the process of formation in recent evolutionary history

  • First Published October 8, 2008
LETTER

Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding

  • First Published September 11, 2008
LETTER

Reduced purifying selection prevails over positive selection in human copy number variant evolution

  • First Published August 7, 2008
LETTER

A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3′ end RNA polyadenylation

  • First Published May 16, 2008
Platypus Special/Letter

Defensins and the convergent evolution of platypus and reptile venom genes

  • First Published May 7, 2008
LETTER

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

  • First Published February 7, 2008
12 | Genomes/Letter

Drosophila genomes" > Evolutionary rate analyses of orthologs and paralogs from 12 Drosophila genomes

  • First Published November 7, 2007
LETTER

Statistical analysis of the genomic distribution and correlation of regulatory elements in the ENCODE regions

  • First Published June 13, 2007
LETTER

Structured RNAs in the ENCODE selected regions of the human genome

  • First Published June 13, 2007
Methods

Mapping of transcription factor binding regions in mammalian cells by ChIP: Comparison of array- and sequencing-based technologies

  • First Published June 13, 2007
Methods

Mapping the chromosomal targets of STAT1 by Sequence Tag Analysis of Genomic Enrichment (STAGE)

  • First Published June 13, 2007
ARTICLE

The DART classification of unannotated transcription within the ENCODE regions: Associating transcription with known and novel loci

  • First Published June 13, 2007
ARTICLE

Integrated analysis of experimental data sets reveals many novel promoters in 1% of the human genome

  • First Published June 13, 2007
PERSPECTIVE

What is a gene, post-ENCODE? History and updated definition

  • First Published June 13, 2007
ARTICLE

Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs

  • First Published March 26, 2007
Methods

Assessing the performance of different high-density tiling microarray strategies for mapping transcribed regions of the human genome

  • First Published November 21, 2006
Methods

Predicting essential genes in fungal genomes

  • First Published August 9, 2006
Methods

Design optimization methods for genomic DNA tiling arrays

  • First Published December 19, 2005
Dog Special/Letters

Hotspots of mutation and breakage in dog and human chromosomes

  • First Published December 8, 2005
RESOURCE

Large-Scale Mutagenesis of the Yeast Genome Using a Tn7-Derived Multipurpose Transposon

  • First Published October 1, 2004
LETTER

Comparative Evolutionary Genomics of Androgen-Binding Protein Genes

  • First Published July 15, 2004
LETTER

Evolution and Comparative Genomics of Odorant- and Pheromone-Associated Genes in Rodents

  • First Published April 1, 2004
LETTER

Occurrence and Consequences of Coding Sequence Insertions and Deletions in Mammalian Genomes

  • First Published April 1, 2004
LETTER

Elevated Rates of Protein Secretion, Evolution, and Disease Among Tissue-Specific Genes

  • First Published January 5, 2004
LETTER

Predicting Protein Cellular Localization Using a Domain Projection Method

  • First Published August 1, 2002
LETTER

Systematic Identification of Novel Protein Domain Families Associated with Nuclear Functions

  • First Published January 1, 2002
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