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Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

  • Myungjin Jo
  • Ah Young Chung
  • Nozomu Yachie
  • Minchul Seo
  • Hyejin Jeon
  • Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
  • ... [+4 authors] ...,
  • Marc Vidal
  • Hae Chul Park
  • Frederick P. Roth
  • Kyoungho Suk
  • First Published June 8, 2017
Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

  • Song Sun
  • Fan Yang
  • Guihong Tan
  • Michael Costanzo
  • Rose Oughtred
  • Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
  • ... [+10 authors] ...,
  • Brenda J. Andrews
  • Charles Boone
  • Kara Dolinski
  • Frederick P. Roth
  • First Published March 14, 2016
Research

ZAK as a cause of limb defects in humans and mice" > Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice

  • Malte Spielmann
  • Naseebullah Kakar
  • Naeimeh Tayebi
  • Catherine Leettola
  • Gudrun Nürnberg
  • Nadine Sowada Darío G. Lupiáñez Izabela Harabula Ricarda Flöttmann Denise Horn Wing Lee Chan Lars Wittler Rüstem Yilmaz Janine Altmüller Holger Thiele Hans van Bokhoven Charles E. Schwartz Peter Nürnberg James U. Bowie
  • ... [+14 authors] ...,
  • Jamil Ahmad
  • Christian Kubisch
  • Stefan Mundlos
  • Guntram Borck
  • First Published January 11, 2016
Research

Coding exons function as tissue-specific enhancers of nearby genes

  • Ramon Y. Birnbaum
  • E. Josephine Clowney
  • Orly Agamy
  • Mee J. Kim
  • Jingjing Zhao
  • Takayuki Yamanaka Zachary Pappalardo Shoa L. Clarke Aaron M. Wenger Loan Nguyen Fiorella Gurrieri David B. Everman Charles E. Schwartz
  • ... [+8 authors] ...,
  • Ohad S. Birk
  • Gill Bejerano
  • Stavros Lomvardas
  • Nadav Ahituv
  • First Published March 22, 2012
Research

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

  • Weisheng Wu
  • Yong Cheng
  • Cheryl A. Keller
  • Jason Ernst
  • Swathi Ashok Kumar
  • Tejaswini Mishra Christapher Morrissey Christine M. Dorman Kuan-Bei Chen Daniela Drautz Belinda Giardine Yoichiro Shibata Lingyun Song Max Pimkin Gregory E. Crawford Terrence S. Furey Manolis Kellis Webb Miller James Taylor Stephan C. Schuster Yu Zhang
  • ... [+16 authors] ...,
  • Francesca Chiaromonte
  • Gerd A. Blobel
  • Mitchell J. Weiss
  • Ross C. Hardison
  • First Published July 27, 2011
Method

Genome-wide identification of conserved regulatory function in diverged sequences

  • Leila Taher
  • David M. McGaughey
  • Samantha Maragh
  • Ivy Aneas
  • Seneca L. Bessling
  • Webb Miller
  • Marcelo A. Nobrega
  • Andrew S. McCallion
  • Ivan Ovcharenko
  • First Published May 31, 2011
Article

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

  • Yong Cheng
  • Weisheng Wu
  • Swathi Ashok Kumar
  • Duonan Yu
  • Wulan Deng
  • Tamara Tripic David C. King Kuan-Bei Chen Ying Zhang Daniela Drautz Belinda Giardine Stephan C. Schuster Webb Miller Francesca Chiaromonte
  • ... [+9 authors] ...,
  • Yu Zhang
  • Gerd A. Blobel
  • Mitchell J. Weiss
  • Ross C. Hardison
  • First Published November 3, 2009
Resource

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

  • Kourosh Salehi-Ashtiani
  • Chenwei Lin
  • Tong Hao
  • Yun Shen
  • David Szeto
  • Xinping Yang Lila Ghamsari HanJoo Lee Changyu Fan Ryan R. Murray Stuart Milstein Nenad Svrzikapa
  • ... [+7 authors] ...,
  • Michael E. Cusick
  • Frederick P. Roth
  • David E. Hill
  • Marc Vidal
  • First Published October 2, 2009
Resource

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

  • Gabriel Markson
  • Christina Kiel
  • Russell Hyde
  • Stephanie Brown
  • Panagoula Charalabous
  • Anja Bremm Jennifer Semple Jonathan Woodsmith Simon Duley Kourosh Salehi-Ashtiani Marc Vidal
  • ... [+6 authors] ...,
  • David Komander
  • Luis Serrano
  • Paul Lehner
  • Christopher M. Sanderson
  • First Published June 23, 2009
Methods

A method for rapid, targeted CNV genotyping identifies rare variants associated with neurocognitive disease

  • Heather C. Mefford
  • Gregory M. Cooper
  • Troy Zerr
  • Joshua D. Smith
  • Carl Baker
  • Neil Shafer Erik C. Thorland
  • ... [+2 authors] ...,
  • Cindy Skinner
  • Charles E. Schwartz
  • Deborah A. Nickerson
  • Evan E. Eichler
  • First Published June 8, 2009
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