Research
Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation
- First Published December 5, 2024
Method
Simultaneous assessment of human genome and methylome data in a single experiment using limited deamination of methylated cytosine
- First Published June 10, 2024
Method
Methyl-SNP-seq reveals dual readouts of methylome and variome at molecule resolution while enabling target enrichment
- First Published November 4, 2022
Method
Comprehensive determination of transcription start sites derived from all RNA polymerases using ReCappable-seq
- First Published November 23, 2021
Method
Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA
- First Published June 17, 2021
Research
High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma
- First Published June 27, 2019
Method
TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data
- First Published July 24, 2014
Method
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
- First Published June 26, 2013
Method
Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods
- First Published June 26, 2013