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Resource

Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease

  • Kangli Wang
  • Weikun Xia
  • Yingli Gu
  • Songpeng Zu
  • Qian Yang
  • Maria Luisa Amaral Yaozhi Wang
  • ... [+2 authors] ...,
  • Allen Wang
  • Xiang-Dong Fu
  • William C. Mobley
  • Bing Ren
  • First Published March 4, 2026
Research

KDM1A maintains genome-wide homeostasis of transcriptional enhancers

  • Saurabh Agarwal
  • Katherine M. Bonefas
  • Patricia M. Garay
  • Emily Brookes
  • Yumie Murata-Nakamura
  • Robert S. Porter
  • Todd S. Macfarlan
  • Bing Ren
  • Shigeki Iwase
  • First Published January 7, 2021
Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

  • Myungjin Jo
  • Ah Young Chung
  • Nozomu Yachie
  • Minchul Seo
  • Hyejin Jeon
  • Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
  • ... [+4 authors] ...,
  • Marc Vidal
  • Hae Chul Park
  • Frederick P. Roth
  • Kyoungho Suk
  • First Published June 8, 2017
Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

  • Song Sun
  • Fan Yang
  • Guihong Tan
  • Michael Costanzo
  • Rose Oughtred
  • Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
  • ... [+10 authors] ...,
  • Brenda J. Andrews
  • Charles Boone
  • Kara Dolinski
  • Frederick P. Roth
  • First Published March 14, 2016
Method

A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening

  • Yarui Diao
  • Bin Li
  • Zhipeng Meng
  • Inkyung Jung
  • Ah Young Lee
  • Jesse Dixon
  • ... [+1 authors] ...,
  • Lenka Maliskova
  • Kun-liang Guan
  • Yin Shen
  • Bing Ren
  • First Published January 26, 2016
Research

Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis

  • Catia Attanasio
  • Alex S. Nord
  • Yiwen Zhu
  • Matthew J. Blow
  • Simon C. Biddie
  • Eric M. Mendenhall Jesse Dixon Crystal Wright Roya Hosseini Jennifer A. Akiyama Amy Holt Ingrid Plajzer-Frick Malak Shoukry Veena Afzal Bing Ren
  • ... [+10 authors] ...,
  • Bradley E. Bernstein
  • Edward M. Rubin
  • Axel Visel
  • Len A. Pennacchio
  • First Published April 21, 2014
Research

cis-mediated silencing in somatic cells" > Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cells

  • Timothy J. Looney
  • Li Zhang
  • Chih-Hsin Chen
  • Jae Hyun Lee
  • Sheila Chari
  • Frank Fuxiang Mao Mattia Pelizzola Lu Zhang Ryan Lister Samuel W. Baker Croydon J. Fernandes Jedidiah Gaetz Kara M. Foshay Kayla L. Clift Zhenyu Zhang Wei-Qiang Li Eric J. Vallender Ulrich Wagner Jane Yuxia Qin Katelyn J. Michelini Branimir Bugarija Donghyun Park Emmanuel Aryee Thomas Stricker Jie Zhou Kevin P. White Bing Ren
  • ... [+22 authors] ...,
  • Gary P. Schroth
  • Joseph R. Ecker
  • Andy Peng Xiang
  • Bruce T. Lahn
  • First Published December 5, 2013
Research

CBX3 regulates efficient RNA processing genome-wide

  • Andrea Smallwood
  • Gary C. Hon
  • Fulai Jin
  • Ryan E. Henry
  • Joaquín M. Espinosa
  • Bing Ren
  • First Published June 8, 2012
Research

Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer

  • Gary C. Hon
  • R. David Hawkins
  • Otavia L. Caballero
  • Christine Lo
  • Ryan Lister
  • Mattia Pelizzola Armand Valsesia Zhen Ye Samantha Kuan Lee E. Edsall Anamaria Aranha Camargo Brian J. Stevenson Joseph R. Ecker
  • ... [+8 authors] ...,
  • Vineet Bafna
  • Robert L. Strausberg
  • Andrew J. Simpson
  • Bing Ren
  • First Published December 7, 2011
Resource

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

  • Kourosh Salehi-Ashtiani
  • Chenwei Lin
  • Tong Hao
  • Yun Shen
  • David Szeto
  • Xinping Yang Lila Ghamsari HanJoo Lee Changyu Fan Ryan R. Murray Stuart Milstein Nenad Svrzikapa
  • ... [+7 authors] ...,
  • Michael E. Cusick
  • Frederick P. Roth
  • David E. Hill
  • Marc Vidal
  • First Published October 2, 2009
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