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Research

CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain" > Mutational scanning of CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain

  • James L. Shepherdson
  • David M. Granas
  • Jie Li
  • Zara Shariff
  • Stephen P. Plassmeyer
  • Alex S. Holehouse
  • Michael A. White
  • Barak A. Cohen
  • First Published September 25, 2024
Resource

Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

  • Guanjue Xiang
  • Xi He
  • Belinda M. Giardine
  • Kathryn J. Isaac
  • Dylan J. Taylor
  • Rajiv C. McCoy Camden Jansen Cheryl A. Keller Alexander Q. Wixom April Cockburn Amber Miller Qian Qi Yanghua He Yichao Li Jens Lichtenberg Elisabeth F. Heuston Stacie M. Anderson Jing Luan Marit W. Vermunt Feng Yue Michael E.G. Sauria Michael C. Schatz James Taylor Berthold Göttgens Jim R. Hughes Douglas R. Higgs Mitchell J. Weiss Yong Cheng Gerd A. Blobel David M. Bodine
  • ... [+25 authors] ...,
  • Yu Zhang
  • Qunhua Li
  • Shaun Mahony
  • Ross C. Hardison
  • First Published July 1, 2024
Research

CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors" > Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors

  • James L. Shepherdson
  • Ryan Z. Friedman
  • Yiqiao Zheng
  • Chi Sun
  • Inez Y. Oh
  • David M. Granas
  • Barak A. Cohen
  • Shiming Chen
  • Michael A. White
  • First Published February 14, 2024
Research

Functional characterization of enhancer activity during a long terminal repeat's evolution

  • Alan Y. Du
  • Xiaoyu Zhuo
  • Vasavi Sundaram
  • Nicholas O. Jensen
  • Hemangi G. Chaudhari
  • Nancy L. Saccone
  • Barak A. Cohen
  • Ting Wang
  • First Published October 3, 2022
Method

Domain-adaptive neural networks improve cross-species prediction of transcription factor binding

  • Kelly Cochran
  • Divyanshi Srivastava
  • Avanti Shrikumar
  • Akshay Balsubramani
  • Ross C. Hardison
  • Anshul Kundaje
  • Shaun Mahony
  • First Published January 18, 2022
Research

Genomic environments scale the activities of diverse core promoters

  • Clarice K.Y. Hong
  • Barak A. Cohen
  • First Published December 27, 2021
Resource

An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis

  • Guanjue Xiang
  • Cheryl A. Keller
  • Elisabeth Heuston
  • Belinda M. Giardine
  • Lin An
  • Alexander Q. Wixom Amber Miller April Cockburn Michael E.G. Sauria Kathryn Weaver Jens Lichtenberg Berthold Göttgens Qunhua Li David Bodine Shaun Mahony James Taylor Gerd A. Blobel Mitchell J. Weiss Yong Cheng Feng Yue
  • ... [+15 authors] ...,
  • Jim Hughes
  • Douglas R. Higgs
  • Yu Zhang
  • Ross C. Hardison
  • First Published March 4, 2020
Research

cis-regulatory activity" > Local sequence features that influence AP-1 cis-regulatory activity

  • Hemangi G. Chaudhari
  • Barak A. Cohen
  • First Published January 5, 2018
Method

HiCRep: assessing the reproducibility of Hi-C data using a stratum-adjusted correlation coefficient

  • Tao Yang
  • Feipeng Zhang
  • Galip Gürkan Yardımcı
  • Fan Song
  • Ross C. Hardison
  • William Stafford Noble
  • Feng Yue
  • Qunhua Li
  • First Published August 30, 2017
Research

cis-regulation in embryonic stem cells" > Interactions between pluripotency factors specify cis-regulation in embryonic stem cells

  • Chris Fiore
  • Barak A. Cohen
  • First Published April 15, 2016
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