Your search for returned 33 results

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Research

CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain" > Mutational scanning of CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain

  • First Published September 25, 2024
Research

CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors" > Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors

  • First Published February 14, 2024
Method

Accurate sequencing of DNA motifs able to form alternative (non-B) structures

  • First Published July 11, 2023
Research

Functional characterization of enhancer activity during a long terminal repeat's evolution

  • First Published October 3, 2022
Research

Genomic environments scale the activities of diverse core promoters

  • First Published December 27, 2021
Research

Selection and thermostability suggest G-quadruplexes are novel functional elements of the human genome

  • First Published June 29, 2021
Research

Long-read sequencing technology indicates genome-wide effects of non-B DNA on polymerization speed and error rate

  • First Published November 6, 2018
Research

cis-regulatory activity" > Local sequence features that influence AP-1 cis-regulatory activity

  • First Published January 5, 2018
Corrigendum

Corrigendum: A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome?

  • First Published October 3, 2016
Research

Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

  • First Published October 20, 2015
Research

High-throughput functional testing of ENCODE segmentation predictions

  • First Published July 17, 2014
Method

Massively parallel synthetic promoter assays reveal the in vivo effects of binding site variants

  • First Published August 6, 2013
Research

A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome?

  • First Published March 28, 2012
Research

A matter of life or death: How microsatellites emerge in and vanish from the human genome

  • First Published October 12, 2011
Research

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

  • First Published July 27, 2011
Research

TATA is a modular component of synthetic promoters

  • First Published July 13, 2010
Article

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

  • First Published November 3, 2009
Resource

Windshield splatter analysis with the Galaxy metagenomic pipeline

  • First Published October 9, 2009
Letter

Ride the wavelet: A multiscale analysis of genomic contexts flanking small insertions and deletions

  • First Published June 5, 2009
LETTER

Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif

  • First Published September 25, 2008
LETTER

The genome-wide determinants of human and chimpanzee microsatellite evolution

  • First Published November 21, 2007
LETTER

cis-regulatory elements using comparative genomics: Some lessons from ENCODE data" > Finding cis-regulatory elements using comparative genomics: Some lessons from ENCODE data

  • First Published June 13, 2007
Methods

ESPERR: Learning strong and weak signals in genomic sequence alignments to identify functional elements

  • First Published October 19, 2006
LETTER

cis-regulatory modules" > Experimental validation of predicted mammalian erythroid cis-regulatory modules

  • First Published October 12, 2006
Methods

Discovery, validation, and genetic dissection of transcription factor binding sites by comparative and functional genomics

  • First Published August 2, 2005
Methods

Regulatory Potential Scores From Genome-Wide Three-Way Alignments of Human, Mouse, and Rat

  • First Published April 1, 2004
LETTER

Insertions and Deletions Are Male Biased Too: A Whole-Genome Analysis in Rodents

  • First Published April 1, 2004
ARTICLE

Patterns of Insertions and Their Covariation With Substitutions in the Rat, Mouse, and Human Genomes

  • First Published April 1, 2004
LETTER

Distinguishing Regulatory DNA From Neutral Sites

  • First Published January 1, 2003
LETTER

Gene Length and Proximity to Neighbors Affect Genome-Wide Expression Levels

  • First Published January 1, 2003
ARTICLE

Covariation in Frequencies of Substitution, Deletion, Transposition, and Recombination During Eutherian Evolution

  • First Published January 1, 2003
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