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Method

Accurate estimation of intraspecific microbial gene content variation in metagenomic data with MIDAS v3 and StrainPGC

  • First Published April 10, 2025
Research

CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain" > Mutational scanning of CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain

  • First Published September 25, 2024
Research

CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors" > Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors

  • First Published February 14, 2024
Research

Functional characterization of enhancer activity during a long terminal repeat's evolution

  • First Published October 3, 2022
Research

Genomic environments scale the activities of diverse core promoters

  • First Published December 27, 2021
Research

Sequence determinants of polyadenylation-mediated regulation

  • First Published September 17, 2019
Research

Systematic interrogation of human promoters

  • First Published January 8, 2019
Research

cis-regulatory activity" > Local sequence features that influence AP-1 cis-regulatory activity

  • First Published January 5, 2018
Corrigendum

Corrigendum: Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators

  • First Published March 1, 2017
Research

Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators

  • First Published December 13, 2016
Research

Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

  • First Published October 20, 2015
Research

Noise in gene expression is coupled to growth rate

  • First Published September 9, 2015
Corrigendum

Corrigendum: Unraveling determinants of transcription factor binding outside the core binding site

  • First Published September 1, 2015
Research

Core promoter sequence in yeast is a major determinant of expression level

  • First Published May 12, 2015
Method

Unraveling determinants of transcription factor binding outside the core binding site

  • First Published March 11, 2015
Research

Molecular dissection of the genetic mechanisms that underlie expression conservation in orthologous yeast ribosomal promoters

  • First Published October 7, 2014
Research

High-throughput functional testing of ENCODE segmentation predictions

  • First Published July 17, 2014
Method

Probing the effect of promoters on noise in gene expression using thousands of designed sequences

  • First Published July 16, 2014
Resource

Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach

  • First Published August 15, 2013
Method

Massively parallel synthetic promoter assays reveal the in vivo effects of binding site variants

  • First Published August 6, 2013
Research

Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise

  • First Published February 12, 2013
Research

Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters

  • First Published October 18, 2011
Research

C. elegans" > High nucleosome occupancy is encoded at X-linked gene promoters in C. elegans

  • First Published December 22, 2010
Research

Overlapping codes within protein-coding sequences

  • First Published September 14, 2010
Research

p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy

  • First Published August 17, 2010
Research

TATA is a modular component of synthetic promoters

  • First Published July 13, 2010
Methods

Incorporating nucleosomes into thermodynamic models of transcription regulation

  • First Published May 18, 2009
Methods

cis-regulatory motifs in human core promoters" > Systematic functional characterization of cis-regulatory motifs in human core promoters

  • First Published February 6, 2008
Methods

Discovery, validation, and genetic dissection of transcription factor binding sites by comparative and functional genomics

  • First Published August 2, 2005
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