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Research

Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

  • Raquel Ordoñez
  • Marta Kulis
  • Nuria Russiñol
  • Vicente Chapaprieta
  • Arantxa Carrasco-Leon
  • Beatriz García-Torre Stella Charalampopoulou Guillem Clot Renée Beekman Cem Meydan Martí Duran-Ferrer Núria Verdaguer-Dot Roser Vilarrasa-Blasi Paula Soler-Vila Leire Garate Estíbaliz Miranda Edurne San José-Enériz Juan R. Rodriguez-Madoz Teresa Ezponda Rebeca Martínez-Turrilas Amaia Vilas-Zornoza David Lara-Astiaso Daphné Dupéré-Richer Joost H.A. Martens Halima El-Omri Ruba Y. Taha Maria J. Calasanz Bruno Paiva Jesus San Miguel Paul Flicek Ivo Gut Ari Melnick Constantine S. Mitsiades Jonathan D. Licht Elias Campo
  • ... [+30 authors] ...,
  • Hendrik G. Stunnenberg
  • Xabier Agirre
  • Felipe Prosper
  • Jose I. Martin-Subero
  • First Published August 20, 2020
Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

  • Myungjin Jo
  • Ah Young Chung
  • Nozomu Yachie
  • Minchul Seo
  • Hyejin Jeon
  • Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
  • ... [+4 authors] ...,
  • Marc Vidal
  • Hae Chul Park
  • Frederick P. Roth
  • Kyoungho Suk
  • First Published June 8, 2017
Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

  • Song Sun
  • Fan Yang
  • Guihong Tan
  • Michael Costanzo
  • Rose Oughtred
  • Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
  • ... [+10 authors] ...,
  • Brenda J. Andrews
  • Charles Boone
  • Kara Dolinski
  • Frederick P. Roth
  • First Published March 14, 2016
Research

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers

  • Xabier Agirre
  • Giancarlo Castellano
  • Marien Pascual
  • Simon Heath
  • Marta Kulis
  • Victor Segura Anke Bergmann Anna Esteve Angelika Merkel Emanuele Raineri Lidia Agueda Julie Blanc David Richardson Laura Clarke Avik Datta Nuria Russiñol Ana C. Queirós Renée Beekman Juan R. Rodríguez-Madoz Edurne San José-Enériz Fang Fang Norma C. Gutiérrez José M. García-Verdugo Michael I. Robson Eric C. Schirmer Elisabeth Guruceaga Joost H.A. Martens Marta Gut Maria J. Calasanz Paul Flicek Reiner Siebert Elías Campo Jesús F. San Miguel Ari Melnick
  • ... [+29 authors] ...,
  • Hendrik G. Stunnenberg
  • Ivo G. Gut
  • Felipe Prosper
  • José I. Martín-Subero
  • First Published February 2, 2015
Research

Alu elements during B-cell activation" > DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation

  • Anne Y. Lai
  • Deepak Mav
  • Ruchir Shah
  • Sara A. Grimm
  • Dhiral Phadke
  • Katerina Hatzi Ari Melnick
  • ... [+2 authors] ...,
  • Cissy Geigerman
  • Steve E. Sobol
  • David L. Jaye
  • Paul A. Wade
  • First Published September 6, 2013
Research

Understanding transcriptional regulation by integrative analysis of transcription factor binding data

  • Chao Cheng
  • Roger Alexander
  • Renqiang Min
  • Jing Leng
  • Kevin Y. Yip
  • Joel Rozowsky Koon-Kiu Yan Xianjun Dong Sarah Djebali Yijun Ruan Carrie A. Davis Piero Carninci Timo Lassman Thomas R. Gingeras Roderic Guigó
  • ... [+10 authors] ...,
  • Ewan Birney
  • Zhiping Weng
  • Michael Snyder
  • Mark Gerstein
  • First Published September 5, 2012
Resource

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

  • Jie Wang
  • Jiali Zhuang
  • Sowmya Iyer
  • XinYing Lin
  • Troy W. Whitfield
  • Melissa C. Greven Brian G. Pierce Xianjun Dong Anshul Kundaje Yong Cheng Oliver J. Rando Ewan Birney
  • ... [+7 authors] ...,
  • Richard M. Myers
  • William S. Noble
  • Michael Snyder
  • Zhiping Weng
  • First Published September 5, 2012
Research

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

  • Bum-Kyu Lee
  • Akshay A. Bhinge
  • Anna Battenhouse
  • Ryan M. McDaniell
  • Zheng Liu
  • Lingyun Song Yunyun Ni Ewan Birney
  • ... [+3 authors] ...,
  • Jason D. Lieb
  • Terrence S. Furey
  • Gregory E. Crawford
  • Vishwanath R. Iyer
  • First Published November 16, 2011
Resource

Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

  • Lingyun Song
  • Zhancheng Zhang
  • Linda L. Grasfeder
  • Alan P. Boyle
  • Paul G. Giresi
  • Bum-Kyu Lee Nathan C. Sheffield Stefan Gräf Mikael Huss Damian Keefe Zheng Liu Darin London Ryan M. McDaniell Yoichiro Shibata Kimberly A. Showers Jeremy M. Simon Teresa Vales Tianyuan Wang Deborah Winter Zhuzhu Zhang Neil D. Clarke Ewan Birney
  • ... [+17 authors] ...,
  • Vishwanath R. Iyer
  • Gregory E. Crawford
  • Jason D. Lieb
  • Terrence S. Furey
  • First Published July 12, 2011
Method

Efficient storage of high throughput DNA sequencing data using reference-based compression

  • Markus Hsi-Yang Fritz
  • Rasko Leinonen
  • Guy Cochrane
  • Ewan Birney
  • First Published January 18, 2011
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