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Perspective

The Topological Regulatory Logic of noncoding RNA–mediated gene expression

  • First Published June 17, 2026
Resource

A limited set of transcriptional programs define major cell types

  • First Published July 29, 2020
Resource

Dynamics of microRNA expression during mouse prenatal development

  • First Published October 23, 2019
Method

Read clouds uncover variation in complex regions of the human genome

  • First Published August 18, 2015
Method

Discovery of recurrent structural variants in nasopharyngeal carcinoma

  • First Published November 8, 2013
Research

De novo DNA demethylation and noncoding transcription define active intergenic regulatory elements

  • First Published June 28, 2013
Research

Genome evolution during progression to breast cancer

  • First Published April 8, 2013
Research

The origin, evolution, and functional impact of short insertion–deletion variants identified in 179 human genomes

  • First Published March 11, 2013
Method

Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements

  • First Published September 5, 2012
Research

Understanding transcriptional regulation by integrative analysis of transcription factor binding data

  • First Published September 5, 2012
Resource

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

  • First Published September 5, 2012
Resource

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

  • First Published September 5, 2012
Research

Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs

  • First Published September 5, 2012
Method

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

  • First Published August 30, 2012
Resource

Synthetic spike-in standards for RNA-seq experiments

  • First Published August 4, 2011
Resource

Drosophila cell lines" > The transcriptional diversity of 25 Drosophila cell lines

  • First Published December 22, 2010
Letter

Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes

  • First Published January 12, 2010
Resource

ProPhylER: A curated online resource for protein function and structure based on evolutionary constraint analyses

  • First Published October 21, 2009
LETTER

C. elegans reveals a lack of universal sequence-dictated positioning" > A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning

  • First Published May 13, 2008
LETTER

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

  • First Published February 7, 2008
LETTER

Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders

  • First Published January 29, 2008
LETTER

Structured RNAs in the ENCODE selected regions of the human genome

  • First Published June 13, 2007
ARTICLE

The DART classification of unannotated transcription within the ENCODE regions: Associating transcription with known and novel loci

  • First Published June 13, 2007
ARTICLE

Prominent use of distal 5′ transcription start sites and discovery of a large number of additional exons in ENCODE regions

  • First Published June 13, 2007
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
PERSPECTIVE

Origin of phenotypes: Genes and transcripts

  • First Published June 13, 2007
ARTICLE

De novo discovery of a tissue-specific gene regulatory module in a chordate

  • First Published September 16, 2005
Methods

Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays

  • First Published July 5, 2005
ARTICLE

Distribution and intensity of constraint in mammalian genomic sequence

  • First Published June 17, 2005
Methods

Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human

  • First Published April 1, 2004
LETTER

Characterization of Evolutionary Rates and Constraints in Three Mammalian Genomes

  • First Published April 1, 2004
ARTICLE

Novel RNAs Identified From an In-Depth Analysis of the Transcriptome of Human Chromosomes 21 and 22

  • First Published March 1, 2004
LETTER

Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes

  • First Published May 1, 2003
METHODS

LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA

  • First Published March 12, 2003
LETTER

Partitioning of Tissue Expression Accompanies Multiple Duplications of the Na+/K+ ATPase α Subunit Gene

  • First Published September 20, 2001
METHODS

Flexible Use of High-Density Oligonucleotide Arrays for Single-Nucleotide Polymorphism Discovery and Validation

  • First Published July 12, 2001
LETTER

Mycobacterium tuberculosis " > Comparing Genomes within the Species Mycobacterium tuberculosis

  • First Published April 1, 2001
METHODS

Detection of Deleted Genomic DNA Using a Semiautomated Computational Analysis of GeneChip Data

  • First Published November 21, 2000
RESEARCH

Mycobacterium DNA Arrays" > Simultaneous Genotyping and Species Identification Using Hybridization Pattern Recognition Analysis of Generic Mycobacterium DNA Arrays

  • First Published May 1, 1998
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