Research
Closing the gaps, and improving somatic structural variant analysis and benchmarking using CHM13-T2T
- First Published March 17, 2025
Research
Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation
- First Published December 5, 2024
Method
Read clouds uncover variation in complex regions of the human genome
- First Published August 18, 2015
Method
Discovery of recurrent structural variants in nasopharyngeal carcinoma
- First Published November 8, 2013
Research
The origin, evolution, and functional impact of short insertion–deletion variants identified in 179 human genomes
- First Published March 11, 2013
Method
Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements
- First Published September 5, 2012
Resource
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
- First Published September 5, 2012
Research
Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver
- First Published June 15, 2010
Research
The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance
- First Published April 29, 2010
Letter
Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes
- First Published January 12, 2010
Resource
ProPhylER: A curated online resource for protein function and structure based on evolutionary constraint analyses
- First Published October 21, 2009
LETTER
Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding
- First Published September 11, 2008
RESOURCE
The C. savignyi genetic map and its integration with the reference sequence facilitates insights into chordate genome evolution
- First Published June 2, 2008
Next-Generation DNA Sequencing/Review
The new paradigm of flow cell sequencing
- First Published June 2, 2008
LETTER
A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning
- First Published May 13, 2008
LETTER
Identification and analysis of internal promoters in Caenorhabditis elegans operons
- First Published August 21, 2007
ARTICLE
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome
- First Published June 13, 2007
REVIEW
Locating mammalian transcription factor binding sites: A survey of computational and experimental techniques
- First Published October 19, 2006
ARTICLE
De novo discovery of a tissue-specific gene regulatory module in a chordate
- First Published September 16, 2005
ARTICLE
Distribution and intensity of constraint in mammalian genomic sequence
- First Published June 17, 2005
Methods
Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity
- First Published June 17, 2005
ARTICLE
Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression
- First Published April 18, 2005
Methods
Mapping segmental and sequence variations among laboratory mice using BAC array CGH
- First Published February 1, 2005
LETTER
Noncoding regulatory sequences of Ciona exhibit strong correspondence between evolutionary constraint and functional importance
- First Published November 15, 2004
Methods
Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human
- First Published April 1, 2004
LETTER
Characterization of Evolutionary Rates and Constraints in Three Mammalian Genomes
- First Published April 1, 2004
RESOURCE
Development and Application of a Salmonid EST Database and cDNA Microarray: Data Mining and Interspecific Hybridization Characteristics
- First Published February 12, 2004
RESOURCE
Internet Contig Explorer (iCE)—A Tool for Visualizing Clone Fingerprint Maps
- First Published June 1, 2003
LETTER
Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes
- First Published May 1, 2003
METHODS
LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA
- First Published March 12, 2003
LETTER
Temperature-Regulated Transcription in the Pathogenic Fungus Cryptococcus neoformans
- First Published September 1, 2002
RESOURCE
Physical Maps for Genome Analysis of Serotype A and D Strains of the Fungal Pathogen Cryptococcus neoformans
- First Published August 21, 2002
LETTER
Evidence That Plant-Like Genes in Chlamydia Species Reflect an Ancestral Relationship between Chlamydiaceae, Cyanobacteria, and the Chloroplast
- First Published July 19, 2002
LETTER
Partitioning of Tissue Expression Accompanies Multiple Duplications of the Na+/K+ ATPase α Subunit Gene
- First Published September 20, 2001
ARTICLE
Changes in Gene Expression Associated with Developmental Arrest and Longevity in Caenorhabditis elegans
- First Published July 12, 2001