Research
Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation
- First Published December 5, 2024
Research
High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma
- First Published June 27, 2019
Method
Read clouds uncover variation in complex regions of the human genome
- First Published August 18, 2015
Method
TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data
- First Published July 24, 2014
Method
Discovery of recurrent structural variants in nasopharyngeal carcinoma
- First Published November 8, 2013
Method
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
- First Published June 26, 2013
Method
Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods
- First Published June 26, 2013
Research
The origin, evolution, and functional impact of short insertion–deletion variants identified in 179 human genomes
- First Published March 11, 2013
Method
Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements
- First Published September 5, 2012
Resource
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
- First Published September 5, 2012
Research
Extensive relationship between antisense transcription and alternative splicing in the human genome
- First Published June 30, 2011
Research
Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver
- First Published June 15, 2010
Letter
Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes
- First Published January 12, 2010
Resource
ProPhylER: A curated online resource for protein function and structure based on evolutionary constraint analyses
- First Published October 21, 2009
Methods
Next-generation tag sequencing for cancer gene expression profiling
- First Published June 18, 2009
LETTER
In-depth characterization of the microRNA transcriptome in a leukemia progression model
- First Published October 10, 2008
LETTER
Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding
- First Published September 11, 2008
Methods
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells
- First Published February 19, 2008
LETTER
Caenorhabditis elegans operons" > Identification and analysis of internal promoters in Caenorhabditis elegans operons
- First Published August 21, 2007
ARTICLE
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome
- First Published June 13, 2007
Methods
Large-scale production of SAGE libraries from microdissected tissues, flow-sorted cells, and cell lines
- First Published November 29, 2006
LETTER
Identification by full-coverage array CGH of human DNA copy number increases relative to chimpanzee and gorilla
- First Published December 19, 2005
ARTICLE
De novo discovery of a tissue-specific gene regulatory module in a chordate
- First Published September 16, 2005
Methods
Simple, robust methods for high-throughput nanoliter-scale DNA sequencing
- First Published September 16, 2005
ARTICLE
Distribution and intensity of constraint in mammalian genomic sequence
- First Published June 17, 2005
Methods
Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity
- First Published June 17, 2005
Methods
Systematic Recovery and Analysis of Full-ORF Human cDNA Clones
- First Published October 15, 2004
Methods
Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human
- First Published April 1, 2004
LETTER
Characterization of Evolutionary Rates and Constraints in Three Mammalian Genomes
- First Published April 1, 2004
RESOURCE
Development and Application of a Salmonid EST Database and cDNA Microarray: Data Mining and Interspecific Hybridization Characteristics
- First Published February 12, 2004
RESOURCE
Internet Contig Explorer (iCE)—A Tool for Visualizing Clone Fingerprint Maps
- First Published June 1, 2003
LETTER
Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes
- First Published May 1, 2003
METHODS
LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA
- First Published March 12, 2003
RESOURCE
Cryptococcus neoformans " > Physical Maps for Genome Analysis of Serotype A and D Strains of the Fungal Pathogen Cryptococcus neoformans
- First Published August 21, 2002
LETTER
Partitioning of Tissue Expression Accompanies Multiple Duplications of the Na+/K+ ATPase α Subunit Gene
- First Published September 20, 2001
RESOURCE
An Oligonucleotide Fingerprint Normalized and Expressed Sequence Tag Characterized Zebrafish cDNA Library
- First Published August 16, 2001
ARTICLE
Caenorhabditis elegans " > Changes in Gene Expression Associated with Developmental Arrest and Longevity in Caenorhabditis elegans
- First Published July 12, 2001