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Genome-wide nucleosome and transcription factor responses to genetic perturbations reveal chromatin-mediated mechanisms of transcriptional regulation

  • Kevin Moyung
  • Yulong Li
  • Heather K. MacAlpine
  • Alexander J. Hartemink
  • David M. MacAlpine
  • First Published December 9, 2025

Drosophila melanogaster ovary" > Rapid evolution of piRNA clusters in the Drosophila melanogaster ovary

  • Satyam P. Srivastav
  • Cédric Feschotte
  • Andrew G. Clark
  • First Published May 15, 2024

Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase

  • Boning Chen
  • Heather K. MacAlpine
  • Alexander J. Hartemink
  • David M. MacAlpine
  • First Published December 11, 2023

Linking the dynamics of chromatin occupancy and transcription with predictive models

  • Trung Q. Tran
  • Heather K. MacAlpine
  • Vinay Tripuraneni
  • Sneha Mitra
  • David M. MacAlpine
  • Alexander J. Hartemink
  • First Published April 23, 2021

Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication

  • Vinay Tripuraneni
  • Gonen Memisoglu
  • Heather K. MacAlpine
  • Trung Q. Tran
  • Wei Zhu
  • Alexander J. Hartemink
  • James E. Haber
  • David M. MacAlpine
  • First Published April 2, 2021

Nascent chromatin occupancy profiling reveals locus- and factor-specific chromatin maturation dynamics behind the DNA replication fork

  • Mónica P. Gutiérrez
  • Heather K. MacAlpine
  • David M. MacAlpine
  • First Published June 19, 2019

Drosophila" > Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in Drosophila

  • Robin L. Armstrong
  • Taylor J.R. Penke
  • Brian D. Strahl
  • A. Gregory Matera
  • Daniel J. McKay
  • David M. MacAlpine
  • Robert J. Duronio
  • First Published October 2, 2018

Drosophila" > Evidence for the fixation of gene duplications by positive selection in Drosophila

  • Margarida Cardoso-Moreira
  • J. Roman Arguello
  • Srikanth Gottipati
  • L.G. Harshman
  • Jennifer K. Grenier
  • Andrew G. Clark
  • First Published April 12, 2016

Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations

  • Juan L. Rodriguez-Flores
  • Khalid Fakhro
  • Francisco Agosto-Perez
  • Monica D. Ramstetter
  • Leonardo Arbiza
  • Thomas L. Vincent Amal Robay Joel A. Malek Karsten Suhre Lotfi Chouchane Ramin Badii Ajayeb Al-Nabet Al-Marri Charbel Abi Khalil Mahmoud Zirie Amin Jayyousi Jacqueline Salit
  • ... [+11 authors] ...,
  • Alon Keinan
  • Andrew G. Clark
  • Ronald G. Crystal
  • Jason G. Mezey
  • First Published January 4, 2016

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition

  • Scott A. Lujan
  • Anders R. Clausen
  • Alan B. Clark
  • Heather K. MacAlpine
  • David M. MacAlpine
  • Ewa P. Malc Piotr A. Mieczkowski
  • ... [+2 authors] ...,
  • Adam B. Burkholder
  • David C. Fargo
  • Dmitry A. Gordenin
  • Thomas A. Kunkel
  • First Published September 12, 2014
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