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Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease

Kangli Wang
Weikun Xia
Yingli Gu
Songpeng Zu
Qian Yang
Maria Luisa Amaral Yaozhi Wang
... [+2 authors] ...,
Allen Wang
Xiang-Dong Fu
William C. Mobley
Bing Ren

First Published March 4, 2026

KDM1A maintains genome-wide homeostasis of transcriptional enhancers

Saurabh Agarwal
Katherine M. Bonefas
Patricia M. Garay
Emily Brookes
Yumie Murata-Nakamura
Robert S. Porter
Todd S. Macfarlan
Bing Ren
Shigeki Iwase

First Published January 7, 2021

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

Myungjin Jo
Ah Young Chung
Nozomu Yachie
Minchul Seo
Hyejin Jeon
Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
... [+4 authors] ...,
Marc Vidal
Hae Chul Park
Frederick P. Roth
Kyoungho Suk

First Published June 8, 2017

An extended set of yeast-based functional assays accurately identifies human disease mutations

Song Sun
Fan Yang
Guihong Tan
Michael Costanzo
Rose Oughtred
Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
... [+10 authors] ...,
Brenda J. Andrews
Charles Boone
Kara Dolinski
Frederick P. Roth

First Published March 14, 2016

A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening

Yarui Diao
Bin Li
Zhipeng Meng
Inkyung Jung
Ah Young Lee
Jesse Dixon
... [+1 authors] ...,
Lenka Maliskova
Kun-liang Guan
Yin Shen
Bing Ren

First Published January 26, 2016

Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis

Catia Attanasio
Alex S. Nord
Yiwen Zhu
Matthew J. Blow
Simon C. Biddie
Eric M. Mendenhall Jesse Dixon Crystal Wright Roya Hosseini Jennifer A. Akiyama Amy Holt Ingrid Plajzer-Frick Malak Shoukry Veena Afzal Bing Ren
... [+10 authors] ...,
Bradley E. Bernstein
Edward M. Rubin
Axel Visel
Len A. Pennacchio

First Published April 21, 2014

cis-mediated silencing in somatic cells" > Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cells

Timothy J. Looney
Li Zhang
Chih-Hsin Chen
Jae Hyun Lee
Sheila Chari
Frank Fuxiang Mao Mattia Pelizzola Lu Zhang Ryan Lister Samuel W. Baker Croydon J. Fernandes Jedidiah Gaetz Kara M. Foshay Kayla L. Clift Zhenyu Zhang Wei-Qiang Li Eric J. Vallender Ulrich Wagner Jane Yuxia Qin Katelyn J. Michelini Branimir Bugarija Donghyun Park Emmanuel Aryee Thomas Stricker Jie Zhou Kevin P. White Bing Ren
... [+22 authors] ...,
Gary P. Schroth
Joseph R. Ecker
Andy Peng Xiang
Bruce T. Lahn

First Published December 5, 2013

CBX3 regulates efficient RNA processing genome-wide

Andrea Smallwood
Gary C. Hon
Fulai Jin
Ryan E. Henry
Joaquín M. Espinosa
Bing Ren

First Published June 8, 2012

Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer

Gary C. Hon
R. David Hawkins
Otavia L. Caballero
Christine Lo
Ryan Lister
Mattia Pelizzola Armand Valsesia Zhen Ye Samantha Kuan Lee E. Edsall Anamaria Aranha Camargo Brian J. Stevenson Joseph R. Ecker
... [+8 authors] ...,
Vineet Bafna
Robert L. Strausberg
Andrew J. Simpson
Bing Ren

First Published December 7, 2011

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

Kourosh Salehi-Ashtiani
Chenwei Lin
Tong Hao
Yun Shen
David Szeto
Xinping Yang Lila Ghamsari HanJoo Lee Changyu Fan Ryan R. Murray Stuart Milstein Nenad Svrzikapa
... [+7 authors] ...,
Michael E. Cusick
Frederick P. Roth
David E. Hill
Marc Vidal

First Published October 2, 2009

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