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Method

Genealogy-based trait association with LOCATER boosts power at loci with allelic heterogeneity

  • Xinxin Wang
  • Ryan Christ
  • Erica Young
  • Chul Joo Kang
  • Indraniel Das
  • Edward A. Belter Markku Laakso
  • ... [+2 authors] ...,
  • Louis J.M. Aslett
  • David Steinsaltz
  • Nathan O. Stitziel
  • Ira M. Hall
  • First Published April 16, 2026
Method

Simultaneous modeling of chromatin conformation changes from multiple single-cell interaction maps with ChromMovie

  • Krzysztof H. Banecki
  • Haoxi Chai
  • Yijun Ruan
  • Dariusz Plewczynski
  • First Published April 8, 2026
Resource

Whole-genome sequencing of diverse 351 cultured prokaryotes including as-yet-unsequenced type strains

  • Shingo Kato
  • Sachiko Masuda
  • Arisa Shibata
  • Takashi Itoh
  • Mitsuo Sakamoto
  • Ken Shirasu
  • Moriya Ohkuma
  • First Published April 7, 2026
Research

Dynamics and consequences of differential RNA isoform production during cardiomyocyte fate determination and early-stage maturation

  • Joanna Delimata-Raczek
  • Natalia Koralewska
  • Bart Krist
  • Magdalena Rakoczy
  • Marek Figlerowicz
  • Ireneusz Stolarek
  • First Published April 3, 2026
Method

High-fidelity bidirectional translation between single-cell transcriptomes and DNA methylomes with scBOND

  • Kehan Lang
  • Chenyang Jia
  • Siyu Li
  • Yi Guo
  • Dingjun Hu
  • Shengquan Chen
  • First Published March 26, 2026
Research

ACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells

  • Elina Abaev-Schneiderman
  • Linh Nguyen
  • Raz Shalev
  • Tzofit Elbaz Biton
  • Anand Chopra
  • Giritharan Jagadeesan Daniel Sevilla-Sanchez Nili Tickotsky Moskovitz
  • ... [+3 authors] ...,
  • Liron Levin
  • Michal Feldman
  • Capucine Van Rechem
  • Dan Levy
  • First Published March 25, 2026
Research

Centromeric instability and chromoanasynthesis observed in nine supernumerary marker chromosomes resolved with long-read genome sequencing

  • Kristine Bilgrav Saether
  • Angelo Salazar Mantero
  • Marlene Ek
  • Maria Pettersson
  • Elisabeth Syk Lundberg
  • Christopher M. Grochowski
  • Claudia M.B. Carvalho
  • Jesper Eisfeldt
  • Anna Lindstrand
  • First Published March 25, 2026
Research

Aphelenchus avenae implicates P5CS in nematode desiccation stress response" > Haplotype-resolved telomere-to-telomere genome of Aphelenchus avenae implicates P5CS in nematode desiccation stress response

  • Yali Zhang
  • Yayi Zhou
  • Yangyang Chen
  • Xueyu Wang
  • Boyan Hu
  • Shahid Siddique Romnick A. Latina Veronica I. Casey Dexin Bo Yucheng Liao
  • ... [+5 authors] ...,
  • Min Zhang
  • Ming Sun
  • Fengjuan Zhang
  • Dadong Dai
  • First Published March 23, 2026
Method

Complete genetic and epigenetic architecture of D4Z4 macrosatellites in FSHD, BAMS, and reference cohorts with D4Z4End2End

  • Lucinda C. Xiao
  • Ayush Semwal
  • Brianna St John
  • Kathleen Zeglinski
  • Shian Su
  • James Lancaster Shifeng Xue Bruno Reversade
  • ... [+3 authors] ...,
  • Matthew E. Ritchie
  • Frédérique Magdinier
  • Marnie E. Blewitt
  • Quentin Gouil
  • First Published March 23, 2026
Method

Parallel analysis of replication timing, gene expression, and copy number with PARTAGE

  • Lakshana Sruthi Sadu Murari
  • Quinn Dickinson
  • Silvia Meyer-Nava
  • Juan Carlos Rivera-Mulia
  • First Published March 19, 2026
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