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Research

Mitotic chromosomes harbor cell type– and species-specific structural features within a universal loop array conformation

  • Marlies E. Oomen
  • A. Nicole Fox
  • Inma Gonzalez
  • Amandine Molliex
  • Thaleia Papadopoulou
  • Pablo Navarro
  • Job Dekker
  • First Published June 6, 2025
Research

Revisiting chromatin packaging in mouse sperm

  • Qiangzong Yin
  • Chih-Hsiang Yang
  • Olga S. Strelkova
  • Jingyi Wu
  • Yu Sun
  • Sneha Gopalan Liyan Yang Job Dekker
  • ... [+3 authors] ...,
  • Thomas G. Fazzio
  • Xin Zhiguo Li
  • Johan Gibcus
  • Oliver J. Rando
  • First Published December 21, 2023
Research

CTCF sites display cell cycle–dependent dynamics in factor binding and nucleosome positioning

  • Marlies E. Oomen
  • Anders S. Hansen
  • Yu Liu
  • Xavier Darzacq
  • Job Dekker
  • First Published January 17, 2019
Research

Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selection

  • Konstantin Popadin
  • Stephan Peischl
  • Marco Garieri
  • M. Reza Sailani
  • Audrey Letourneau
  • Federico Santoni Samuel W. Lukowski Georgii A. Bazykin Sergey Nikolaev
  • ... [+4 authors] ...,
  • Diogo Meyer
  • Laurent Excoffier
  • Alexandre Reymond
  • Stylianos E. Antonarakis
  • First Published December 13, 2017
Research

SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells

  • A. Rasim Barutcu
  • Bryan R. Lajoie
  • Andrew J. Fritz
  • Rachel P. McCord
  • Jeffrey A. Nickerson
  • Andre J. van Wijnen Jane B. Lian
  • ... [+2 authors] ...,
  • Janet L. Stein
  • Job Dekker
  • Gary S. Stein
  • Anthony N. Imbalzano
  • First Published July 19, 2016
Research

Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin

  • Elizabeth Ing-Simmons
  • Vlad C. Seitan
  • Andre J. Faure
  • Paul Flicek
  • Thomas Carroll
  • Job Dekker
  • Amanda G. Fisher
  • Boris Lenhard
  • Matthias Merkenschlager
  • First Published February 12, 2015
Research

BRF1 mutations alter RNA polymerase III–dependent transcription and cause neurodevelopmental anomalies" > BRF1 mutations alter RNA polymerase III–dependent transcription and cause neurodevelopmental anomalies

  • Guntram Borck
  • Friederike Hög
  • Maria Lisa Dentici
  • Perciliz L. Tan
  • Nadine Sowada
  • Ana Medeira Lucie Gueneau Holger Thiele Maria Kousi Francesca Lepri Larissa Wenzeck Ian Blumenthal Antonio Radicioni Tito Livio Schwarzenberg Barbara Mandriani Rita Fischetto Deborah J. Morris-Rosendahl Janine Altmüller Alexandre Reymond Peter Nürnberg Giuseppe Merla
  • ... [+16 authors] ...,
  • Bruno Dallapiccola
  • Nicholas Katsanis
  • Patrick Cramer
  • Christian Kubisch
  • First Published January 5, 2015
Research

Novel H3K4me3 marks are enriched at human- and chimpanzee-specific cytogenetic structures

  • Giuliana Giannuzzi
  • Eugenia Migliavacca
  • Alexandre Reymond
  • First Published June 10, 2014
Research

Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments

  • Vlad C. Seitan
  • Andre J. Faure
  • Ye Zhan
  • Rachel Patton McCord
  • Bryan R. Lajoie
  • Elizabeth Ing-Simmons Boris Lenhard Luca Giorgetti Edith Heard
  • ... [+4 authors] ...,
  • Amanda G. Fisher
  • Paul Flicek
  • Job Dekker
  • Matthias Merkenschlager
  • First Published September 3, 2013
Research

Correlated alterations in genome organization, histone methylation, and DNA–lamin A/C interactions in Hutchinson-Gilford progeria syndrome

  • Rachel Patton McCord
  • Ashley Nazario-Toole
  • Haoyue Zhang
  • Peter S. Chines
  • Ye Zhan
  • Michael R. Erdos
  • Francis S. Collins
  • Job Dekker
  • Kan Cao
  • First Published November 14, 2012
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