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Method

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

Jonathan S. Brammeld
Mia Petljak
Inigo Martincorena
Steven P. Williams
Luz Garcia Alonso
Alba Dalmases Beatriz Bellosillo Carla Daniela Robles-Espinoza Stacey Price Syd Barthorpe Patrick Tarpey Constantine Alifrangis Graham Bignell Joana Vidal Jamie Young Lucy Stebbings Kathryn Beal Michael R. Stratton Julio Saez-Rodriguez
... [+14 authors] ...,
Mathew Garnett
Clara Montagut
Francesco Iorio
Ultan McDermott

First Published February 8, 2017

Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

Song Sun
Fan Yang
Guihong Tan
Michael Costanzo
Rose Oughtred
Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
... [+10 authors] ...,
Brenda J. Andrews
Charles Boone
Kara Dolinski
Frederick P. Roth

First Published March 14, 2016

Method

Estimation of rearrangement phylogeny for cancer genomes

Chris D. Greenman
Erin D. Pleasance
Scott Newman
Fengtang Yang
Beiyuan Fu
Serena Nik-Zainal David Jones King Wai Lau Nigel Carter
... [+4 authors] ...,
Paul A.W. Edwards
P. Andrew Futreal
Michael R. Stratton
Peter J. Campbell

First Published October 12, 2011