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Method

Optimizing nanopore adaptive sampling for pneumococcal serotype surveillance in complex samples using the graph-based GNASTy algorithm

  • Samuel T. Horsfield
  • Basil C.T. Fok
  • Yuhan Fu
  • Paul Turner
  • John A. Lees
  • Nicholas J. Croucher
  • First Published March 4, 2025
Method

k-mer analysis" > Seamless, rapid, and accurate analyses of outbreak genomic data using split k-mer analysis

  • Romain Derelle
  • Johanna von Wachsmann
  • Tommi Mäklin
  • Joel Hellewell
  • Timothy Russell
  • Ajit Lalvani
  • ... [+1 authors] ...,
  • Leonid Chindelevitch
  • Nicholas J. Croucher
  • Simon R. Harris
  • John A. Lees
  • First Published October 15, 2024
Method

Pangenome-spanning epistasis and coselection analysis via de Bruijn graphs

  • Juri Kuronen
  • Samuel T. Horsfield
  • Anna K. Pöntinen
  • Sudaraka Mallawaarachchi
  • Sergio Arredondo-Alonso
  • Harry Thorpe Rebecca A. Gladstone Rob J.L. Willems Stephen D. Bentley Nicholas J. Croucher
  • ... [+5 authors] ...,
  • Johan Pensar
  • John A. Lees
  • Gerry Tonkin-Hill
  • Jukka Corander
  • First Published August 12, 2024
Method

Accurate and fast graph-based pangenome annotation and clustering with ggCaller

  • Samuel T. Horsfield
  • Gerry Tonkin-Hill
  • Nicholas J. Croucher
  • John A. Lees
  • First Published August 24, 2023
Method

Genealogical inference and more flexible sequence clustering using iterative-PopPUNK

  • Bin Zhao
  • John A. Lees
  • Hongjin Wu
  • Chao Yang
  • Daniel Falush
  • First Published May 30, 2023
Method

Multi–cell type gene coexpression network analysis reveals coordinated interferon response and cross–cell type correlations in systemic lupus erythematosus

  • Bharat Panwar
  • Benjamin J. Schmiedel
  • Shu Liang
  • Brandie White
  • Enrique Rodriguez
  • Kenneth Kalunian Andrew J. McKnight
  • ... [+2 authors] ...,
  • Rachel Soloff
  • Gregory Seumois
  • Pandurangan Vijayanand
  • Ferhat Ay
  • First Published March 5, 2021
Method

Profiling the long noncoding RNA interaction network in the regulatory elements of target genes by chromatin in situ reverse transcription sequencing

  • Shilin Zhang
  • Yichen Wang
  • Lin Jia
  • Xue Wen
  • Zhonghua Du
  • Cong Wang Yajing Hao Dehai Yu Lei Zhou Naifei Chen Jingcheng Chen Huiling Chen Hui Zhang Ilkay Celik Günhan Gülsoy Jianjun Luo Baoming Qin Xueling Cui Zhonghui Liu Songling Zhang Miguel A. Esteban Ferhat Ay Wei Xu Runsheng Chen
  • ... [+19 authors] ...,
  • Wei Li
  • Andrew R. Hoffman
  • Ji-Fan Hu
  • Jiuwei Cui
  • First Published July 17, 2019
Method

Fast and flexible bacterial genomic epidemiology with PopPUNK

  • John A. Lees
  • Simon R. Harris
  • Gerry Tonkin-Hill
  • Rebecca A. Gladstone
  • Stephanie W. Lo
  • Jeffrey N. Weiser
  • Jukka Corander
  • Stephen D. Bentley
  • Nicholas J. Croucher
  • First Published January 24, 2019
Method

Joint annotation of chromatin state and chromatin conformation reveals relationships among domain types and identifies domains of cell-type-specific expression

  • Maxwell W. Libbrecht
  • Ferhat Ay
  • Michael M. Hoffman
  • David M. Gilbert
  • Jeffrey A. Bilmes
  • William Stafford Noble
  • First Published February 12, 2015
Method

Statistical confidence estimation for Hi-C data reveals regulatory chromatin contacts

  • Ferhat Ay
  • Timothy L. Bailey
  • William Stafford Noble
  • First Published February 5, 2014
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