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Method

A comparison of ancient DNA yields across ossicles and the petrous bone reveals the best preservation in the stapes and incus

  • Ekin Sağlıcan
  • Arda Sevkar
  • Duygu Deniz Kazancı
  • Gonzalo Oteo García
  • Sevgi Yorulmaz
  • Kıvılcım Başak Vural Gökhan Çakan Gökçen Adiloğlu Duru Buldak Güneş Duru Aliye Öztan Brenna Hassett Nurcan Kayacan Aslı Erim Özdoğan Anders Götherström
  • ... [+10 authors] ...,
  • Füsun Özer
  • Ömür Dilek Erdal
  • Yılmaz Selim Erdal
  • Mehmet Somel
  • First Published June 11, 2026
Method

Reference-informed spatial domain detection using weak supervision for spatial transcriptomics

  • Xin Ma
  • Weijia Jin
  • Qing Lu
  • Ramon C. Sun
  • Li Chen
  • First Published June 3, 2026
Method

Transfer learning enhances clinical utility of polygenic scores with small, phenotypically refined cohorts

  • YuChung Lin
  • Christoph Patrick Beier
  • Zuzana Sobiskova
  • Hamandi Khalid
  • Tommy Stodberg
  • Ching Ching Ng Danielle Andrade Marte Roa Syvertsen Elena Gardella Alessandro Orsini Choong Yi Fong Jana Zarubova Michaela Kajsov Kheng Seang Lim Kaja Kristine Selmer Emanuele Cerulli Irelli
  • ... [+11 authors] ...,
  • Guido Rubboli
  • Pasquale Striano
  • Deb K. Pal
  • Lisa J Strug
  • First Published June 2, 2026
Method

Augmenting transcriptome annotations through the lens of splicing evolution

  • Xiaofei Carl Zang
  • Ke Chen
  • Irtesam Mahmud Khan
  • Mingfu Shao
  • First Published May 29, 2026
Method

RECOMBINE identifies recurrent composite markers of cell types and states

  • Xubin Li
  • Justin Nguyen
  • Anil Korkut
  • First Published May 20, 2026
Method

Deep learning the TF regulatory code for gene expression

  • Yuanyuan Li
  • Xiaohui Huang
  • Yixuan Qi
  • Zheng Zhang
  • Hui Ding
  • Quan Zou
  • Li Liu
  • First Published May 15, 2026
Method

Cultivation-independent high-quality microbial genome reconstruction from environmental samples with midi-metagenomics

  • John Vollmers
  • Maximiano Correa Cassal
  • Anne-Kristin Kaster
  • First Published May 15, 2026
Method

Tree reconstruction guarantees from CRISPR-Cas9 lineage tracing data using Neighbor-Joining

  • Kevin An
  • Sebastian Prillo
  • Wilson Wu
  • Ivan Kristanto
  • Matthew G. Jones
  • Yun S. Song
  • Nir Yosef
  • First Published May 14, 2026
Method

Accurate delineation of cellular niches via integrated spatial transcriptomics and histological imaging with SYMOL

  • Daoyuan Wang
  • Fengyi Zhou
  • Wenlan Chen
  • Cheng Liang
  • Fei Guo
  • First Published May 14, 2026
Method

Using CRISPR barcoding as a molecular clock to capture dynamic processes at single-cell resolution

  • Yolanda Andres-Lopez
  • Alice Santambrogio
  • Ioannis Kafetzopoulos
  • Christopher D. Todd
  • Carla El Khouri-Gonzalez
  • J-Elliot Gonzalez-Alvarez
  • ... [+1 authors] ...,
  • Celia Alda-Catalinas
  • Stephen J. Clark
  • Wolf Reik
  • Irene Hernando-Herraez
  • First Published May 1, 2026
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